Kill Biters Console Commands

Stop map-gen from making new biters:
/c local surface = game.player.surface
local mgs = surface.map_gen_settings
mgs.autoplace_controls["enemy-base"].size = "none"
surface.map_gen_settings = mgs

Kill all nests, worms, and walking units:
/c local surface=game.player.surface
for key, entity in pairs(game.surfaces.nauvis.find_entities_filtered({force="enemy"})) do
    entity.destroy()
end

Disable pollution to save UPS
/c game.player.surface.clear_pollution()
game.map_settings.pollution.enabled = false