import sys
from PyQt5.QtWidgets import *


class Example(QWidget):
    def __init__(self):
        super().__init__()
        self.initUI()

    def initUI(self):
        self.symbol = ""
        self.setGeometry(300, 300, 500, 500)
        self.setWindowTitle('Крестики-нолики')

        self.choose = QLabel(self)
        self.choose.setText("Выберите знак")
        self.choose.move(200, 320)

        self.x_radiobutton = QRadioButton("X", self)
        self.x_radiobutton.move(200, 340)
        self.null_radiobutton = QRadioButton("0", self)
        self.null_radiobutton.move(250, 340)
        self.x_radiobutton.clicked.connect(self.x_symbol)
        self.null_radiobutton.clicked.connect(self.null_symbol)


        self.list_buttons = [[QPushButton("", self) for i in range(3)] for j in range(3)]
        for i in range(1, 4):
            for j in range(3):
                self.list_buttons[i - 1][j].resize(100, 100)
                self.list_buttons[i - 1][j].move(i * 100, j * 100)
                self.list_buttons[i - 1][j].clicked.connect(lambda: self.update_button(self.list_buttons[i - 1][j]))

    def update_button(self, button):
        button.setText(self.symbol)

    def x_symbol(self):
        self.symbol = "X"
        self.x_radiobutton.setDisabled(True)
        self.null_radiobutton.setDisabled(True)

    def null_symbol(self):
        self.symbol = "0"
        self.x_radiobutton.setDisabled(True)
        self.null_radiobutton.setDisabled(True)


if __name__ == '__main__':
    app = QApplication(sys.argv)
    ex = Example()
    ex.show()
    sys.exit(app.exec())