function pm_regenerate_custom_permalink($post_ID, $post, $update) {
    global $permalink_manager_uris;

    if($post->post_type == 'courses') {
        $permalink_manager_uris[$post_id] = Permalink_Manager_URI_Functions_Post::get_default_post_uri($post_id);
        update_option('permalink-manager-uris', $permalink_manager_uris);
    }
}
add_action('save_post', 'pm_regenerate_custom_permalink', 111, 3);