Traceback (most recent call last):
  File "C:UsersGuilhermeDesktopdasdsa.py", line 17, in <module>
    conta = (trans1) * trans2
TypeError: can't multiply sequence by non-int of type 'tuple'

import urllib.request

page = urllib.request.urlopen("http://dolarhoje.com/")
text = page.read().decode("utf8")

price = text[9938:9942]

trans1 = (price)
tuple(price)

usertap = input("Coloque o real aqui:")
trans2 = tuple(usertap)
conta = (trans1) * trans2

print(conta)

import urllib.request

page = urllib.request.urlopen("http://dolarhoje.com/")
text = page.read().decode("utf8")

raw_price = text[9938:9942]
# substitui a pontuação e converte para float
price = float(raw_price.replace(',', '.'))

raw_usertap = input("Coloque o real aqui: ")
# o mesmo procedimento feito anteriormente só que com a entrada do usuário
usertap = float(raw_usertap.replace(',', '.'))

conta = price * usertap

print(conta)

trans1 = float(price)
trans2 = float(usertap)

trans1 = Float(price)
trans2 = Float(usertap)