Tricyclic Antidepressant Powder Tianeptine For Brain Health

Tricyclic Antidepressant Powder Tianeptine For Brain Health CAS:66981-73-5

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Tianeptine Description:
Tianeptine, sold under the brand names Stablon and Coaxil among others, is an atypical antidepressant which is used mainly in the treatment of major depressive disorder, although it may also be used to treat anxiety, asthma, and irritable bowel syndrome. In terms of chemical structure, it is technically a tricyclic antidepressant (TCA), but it has a very different drug profile than other TCAs, and is not usually grouped with them.

Tianeptine has antidepressant and anxiolytic effects with a relative lack of sedative, anticholinergic, and cardiovascular side effects.It has been found to act as an atypical agonist of the μ-opioid receptor with clinically negligible effects on the δ- and κ-opioid receptors.μ-Opioid receptor agonists typically induce euphoria, and in accordance, tianeptine does so at high doses well above the normal therapeutic range.


Tianeptine Spec.
Product Name:Tianeptine
Synonyms:TIANEPTINE;7-[(3-chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-yl)-amino]heptanoic acid s,s-dioxide;7-[(3-CHLORO-6,11-DIHYDRO-6-METHYL-DIBENZO[C,F][1,2]THIAZEPINE-11-YL)AMINO]HEPTANOIC ACID S,S DIOXIDE;Tianeptineacid;COAXIL;7-[(3-Chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-y1)amino]heptanoic acid S,S-dioxide;30123-17-2 (Mono-hydrochloride salt);Brn 1232295
CAS:66981-73-5
MF:C21H25ClN2O4S
MW:436.95


HOW DOES TIANEPTINE WORK ?
What makes Tianeptine so effective is that it reduces stress on the brain, both physical and mental. Tianeptine causes stress-induced alterations morphology and synaptic plasticity. As it alleviates stress, it also improved learning, brain cognition and memory, two things often diminished by serious depressive conditions. (Zoldaz & et. al, 2010). Like many drugs, there are still studies and concerns that the efficiency and effectiveness of Tianeptine as a whole is difficult to ascertain. After all, Tianeptine, like many drugs, can have a vastly distinct effect on some people and entirely different one on others. More studies are needed to determine if there is a universal dose or regiment that can produce absolute results .

TIANEPTINE DOSAGE
The recommended dosage of Tianeptine capsules is usually 12-36 mg per day, taken as 12mg individual dosages, one in the morning and one in the afternoon and a final in the evening time. This substance is sold in capsule, tablet and powder form.

Side effects
Compared to other TCAs it produces significantly fewer cardiovascular, anticholinergic (like dry mouth or constipation), sedative and appetite-stimulating effects.A recent review found that it was amongst the antidepressants most prone to causing hepatotoxicity (liver damage), although the evidence to support this concern was of limited quality. Although not well studied with tianeptine, it has been shown for tricyclic antidepressants that they may cause cardiac arrhythmias.

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