$(".mydataTable").dataTable({
      "aoColumnDefs": [
     {"bVisible": false, "aTargets": [ 0 ] }
      ],
     "aaSorting": [[ 0, "desc" ]],
     "bJQueryUI": true,
     "bPaginate": false,
     "bStateSave": true,
     "bInfo": false,
     "aLengthMenu": [5, 10, 15, 25, 50, 100],
     "iDisplayLength" : 10,
     "bAutoWidth" : false,
     "aoColumns": [
    { "sWidth": "70px" },
    { "sWidth": "90px" },
    { "sWidth": "220px"  },
    { "sWidth": "90px"  },
    { "sWidth": "90px"  },
    { "sWidth": "90px"  }
     ],

});

"aoColumnDefs": [
    {"bVisible": false, "aTargets": [ 0 ] },
    { "sWidth": "10%", "aTargets": [ 2 ] }
 ],

<table class="mydataTable" style="width: 650px;">

table#customTable {
    table-layout: fixed;
}