COVID-19 patients can rapidly generate virus-attacking T cel

COVID-19 patients can rapidly generate virus-attacking T cells, shows study

Patients suffering from severe respiratory symptoms as a result of SARS-CoV-2 infection can rapidly generate virus-attacking T cells, and can increase this production over time, suggests a new study of T cells from 10 COVID-19 patients under intensive care treatment.

In addition, 2 out of 10 healthy individuals without prior exposure to the virus harbored SARS-CoV-2-reactive T cells, the researchers found, possibly indicating that these T cells can cross-react to the novel coronavirus due to past infection with related coronaviruses that cause common cold symptoms.

Together, these new data address the poorly understood question of whether SARS-CoV-2-specific T cell responses vary in patients over time depending on disease severity, and helps to answer whether patients with more severe symptoms can generate protective virus-specific T cells at all.
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