Loses Android 17 and 18 after becoming Super Perfect

"I am perfect, both in body and mind. I planned this all. You all recall when Krillin asked me what I had done with Number 17, do you not? I lied when I said I had no idea, though I hadn't considered the scenario until that particular moment. You all nearly destroyed me once before—a closer call than I would have liked, though of course I still lived on. When Goku, along with you all, blasted my Semiperfect body to nothing but a few solitary scraps of tissue, you all effectively killed 17 yourselves. He was gone from my design, his body and spirit dead. And yet, when I regenerated, I appeared just as I was before—stronger even!"

"Uh oh, I think I know where this is going," Trunks whispered.

"That time, I'll admit that my own survival was unexpected—seemingly mere chance, a fortune even I hadn't predicted. But this time, it was all but a surprise to me. Finding myself in great need of Number 18 once again, I realized that my body must keep a memory, a record of some kind which it uses as blueprints when regenerating. Best of all, this blueprint never forgets, and uses only my strongest form in its design."

...

"But my fears were ungrounded, it seems. Though you all knew well my regenerative capabilities, it seems that the lot of you remained completely inept." The monster chuckled at his insult. "Once my vision was again restored, I was able to confirm that I was indeed in my perfect state. Imagine my delight as I felt not only my full strength from before, but a well of new power rising within me—a zenkai, thanks to the brilliant inclusion of Saiyan DNA within my design. I was no longer merely the perfect being...I was something more, new, transcendent...I had become super perfect!"

- Bringer of Death Chapter 75