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- Shock was defined as the requirement of the following vasopressors and inotropes: dopamine ≥ 7.5 μg·kg−1·min−1, dobutamine ≥ 5 μg·kg−1·min−1, norepinephrine ≥ 5 μg·min−1, phenylephrine ≥ 75 μg·min−1, epinephrine at any dose, milrinone at any dose (if used in conjunction with another agent), vasopressin ≥ 0.03 U·min−1 (if used in conjunction with another agent)
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