NoAdTTV

Install Tampermonkey
Homepage: https://www.tampermonkey.net/
Choose Browser

Add Ad Block Script to Tampermonkey
Github: https://github.com/pixeltris/TwitchAdSolutions

Navigate to the "video-swap-new" folder and import the "video-swap-new.user.js" file.

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Install Stylus
Chrome Store: https://chromewebstore.google.com/detail/stylus/clngdbkpkpeebahjckkjfobafhncgmne?hl=en
Firefox Addon: https://addons.mozilla.org/en-US/firefox/addon/styl-us/
Or Github: https://github.com/openstyles/stylus/releases

Open the Stylus Menu and select "Mange Styles"
Click on "Import" on the left and paste the following (save it as "Ad Free Twitch"):

@-moz-document domain("twitch.tv") {
.resize-detector,
div[class*="giftExpirationCallout"]
{
    display: none !important;
}

/* Top Nav - Get Turbo */
.top-nav__menu>.Layout-sc-1xcs6mc-0:nth-of-type(3)>.Layout-sc-1xcs6mc-0:nth-of-type(6)
{
    display: none !important;
}

/* Themed Ads */
div.subtember-gradient, div.holiday-gradient,
.ubo-overlay
{
    display: none !important;
}

#directory-banner[data-a-target="directory-banner-ad-slot"]
{
    display: none !important;
}

/* Inline Stream Overlay Ads */
.stream-display-ad__wrapper,
div[data-a-target="outstream-ax-overlay"],
#directory-rectangle:has(.online-video-ad-container)
{
        display: none !important;
}

div[class^="ScTransitionBase"]:has(div[id="amazon-companion-ad-div"]),
div[class^="InjectLayout-sc"][data-a-target="player-overlay-click-handler"],
.avap-ads-container,
div:has([aria-label="Leave feedback for this ad"]),
div[class^="Layout-sc-"][style^="position: absolute;"]:has([data-a-target="outstream-ax-overlay"])
{
    display: none !important;
}

.video-player--stream-display-ad_lower-third,
.video-ref.video-player--stream-display-ad_squeezeback,
.video-player__overlay, .video-player__container, div[data-a-target="video-ref"],
video
{
    min-height: 100% !important;
    min-width: 100% !important;
    height: 100% !important;
    width: 100% !important;
}

.video-player--stream-display-ad_vertical-video
{
    inset-inline-start: unset !important;
}
}