A combined list of ideas

Restart: Superior Defender OG Force!: A D&D 4e game with mecha characters

Revitalisation: Super Foxhound Wars: Save the free world, or doom it, with super-gadgets, tanks that turn into helicopters, and a winning smile.
Variants: Savage Worlds, Mutants and Masterminds (Agents of Freedom)
Series list may be revised

Super Space Western Wars:
Variants: Savage Worlds, 40K Rogue Trader, Rogue Trader in non-40K setting
Series list:
Setting-wide elements: Adventures of the Galaxy Rangers, Firefly, J9 series, Cowboy Bebop, Outlaw Star, Saber Rider/Bismarck, Jayce and the Wheeled Warriors,
Planets: Xabungle, Trigun, Gun X Sword, Bravestarr, Deep Space Nine, Broncosaurus Rex,
Possible inclusions Pending research.

Kamen Rider
System? (M&M might not be a great option for reasons)
Variants: Eva Rider, All Rider Cosmology
Crossover Potential is high

Toholon: Mad Steampunk Science versus magic and Kaiju
Variants: Savage Worlds, Spirit of the Century.

The Unusual Adventurers: A D&D 3.5 game with a major difference: As much of the material in the core books as possible is banned.

Monsters Inc: A D&D 3.5/Savage Species campaign where the players are monsters, starting ECL 12+.
Variants:
Servants of the Pair: Join the great monster conspiracy to finally overthrow the forces of light and justice that have choked the world for millenia.
Monsters in the Dark: A group of good-aligned creatures, brought together to help unite the world, in a unique fashion.

Dark Q-Resy: You are Acolytes of the infamous Inquisitor Tarask, as she tears the Calixis sector asunder in order to save it.
Variant: Ascension: You are the inquisitors peers.

Kobolton: A D&D 3.5 campaign where the players are all Kobolds, meant to found a new tribe in a dangerous border region. Can you built your Fortress and protect it from the many threats? Can you create wealth, and what will you do with it? What shape will your fortress take, and who will really be in charge of it? And will there be Lava and Carp?

Transformers
You know the premise. Most likely going to be a mix of Western and Japanese G1 and Beast Wars, with parts of Animated and cues from the other series. NO Kiss Players.
Possible Campaign Premises:
1) Repeat the usual setup of a team of a team each of Autobots and Decepticons waking up on Earth and having to continue the war while blending in. Tone negotiable.
2) A darker tone as the Decepticon Empire starts to grip the Galaxy, with Earth as one of the few remaining free worlds. Autobots scramble to find some way to turn the tide.
3) Players are low-ranking Decepticons, trying to survive the war, in as much danger from the politics of their superiors as from the Autobots.
4) Super Energon Wars: As 1, but its an SRW Earth, with human mechs entering the fray and confusing the issue.
5) Transformers land on earth....but a much different earth. I'm thinking Post-apocalypse right now, but other ideas may come to me.
Possible Systems: Almost definitely Mutants and Masterminds, though maybe BESM 3E, and theres a small crazy part of me that wants to try AdEva.

Exalted: Dragonbloods. Not sure on details yet, but a general 'L5R with Exalts' vibe is probably what I'd go for.
- suggestion has been made of Alchemical Magical Girls. Not sure what to make of that

Fallout
System: Dark Heresy, Savage Worlds, D20 modern, Others?
Variants: Sequel to 3 or NV, Hawaii
Crossover Potential?

All Fighters Battle Royale
Series: Street Fighter, KoF, Mortal Kombat, Capcom Vs, Guilty Gear, BlazBlue, Tekken, and very likely more (Such as Soul Calibur, if someone convinces me)

Strike Legion: Supersoldiers fighting against the tyrannical rule of The Empress of Thunderous Fury...

From RPG.net:

Star Wars meets feudal Japan: no aliens, no Force, no empire or rebel alliance - just a bunch of warring planets, a samurai caste trained in lightsaber kenjutsu and telekinesis, and ashigaru soldiers with shiny armor and peculiarly inaccurate blasters.
(I might mod this, aliens aren't so bad, niether is the force or rebels. It all depends on system used. The stuff in Dark Heresy would work really well, you'd be replacing grimdark with Nippon Ichi)


From Haken

Happygundam
My thoughts:...not a bad concept I suppose, but needs fleshing out and a system


From Gill:

Straight-Up M&M
My Thoughts: My issue with any superhero setting is that I have to world-build the fuck out of it. I dislike "Its the normal shitty world except with 5 super people and nothing has changed." I'm far more of a Top Ten type with the ramifications of WW2 supersoldiers, ancient alien dieties and Sorcerors Supreme out there for everyone to see.
Also I'd likely steal an existing setting or even more than one.


From Stealth:

Magical Burst: Er, I guess its a possibility.