47- Sedative Hypo

The Silverballers were invisible beneath the loose zip-up top. His garrote, plus a hypo loaded with an extremely effective sedative, were stashed in a waterproof knapsack that sat beside him.
...

  “I use regular fertilizer,” Mrs. Beasley admitted. “But the key is to pinch off the spent blooms. That makes them flower again.”

  “Well, it certainly works,” 47 said, admiringly. “By the way, might I have a drink of water? I should have brought some, but I forgot, and it’s a long ways back to the dock.”

  The request seemed innocent enough, so Mrs. Beasley said, “Yes, of course. I’ll be right back.” She stepped through a sliding glass door that led into a comfortably furnished living room and the small galley-style kitchen beyond.

  A moment later he found her there, removing a bottle of chilled water from her refrigerator. A large hand closed over mouth. Mrs. Beasley tried to scream, felt something bite her neck, and instantly began to fall.

  Agent 47 caught the unconscious woman and carried her into the single bedroom, where he laid her out on the neatly made bed. To make doubly sure that she would remain immobilized for the necessary length of time, he bound her wrists and ankles with some of her own nylons. Confident that the elderly woman wasn’t about to go anywhere, he set about his real task, which was to enter the neighboring houseboat and have a chat with its owner.

- Hitman: Enemy Within, Chapter 4