documentclass{article}
usepackage{fontspec}
usepackage{microtype}
usepackage{lipsum}

defaultfontfeatures{ Scale=MatchLowercase }
setmainfont{Georgia}[Scale = 1.0]

begin{document}
  lipsum
end{document}

documentclass[varwidth,preview]{standalone}
usepackage{amsmath}
usepackage[math-style=ISO]{unicode-math}
usepackage{microtype}

defaultfontfeatures{ Scale=MatchLowercase }
setmainfont{Georgia}[Scale = 1.0]
setmathfont{Asana Math}
setmathfont[range={up,`∏,`∑,`∙,`√,`∞},
             script-features={}, sscript-features={}
            ]{Georgia}
setmathfont[range=it,
             script-features={}, sscript-features={}
            ]{Georgia Italic}
setmathfont[range=bfup,
             script-features={}, sscript-features={}
            ]{Georgia Bold}
setmathfont[range=bfit,
             script-features={}, sscript-features={}
            ]{Georgia Bold Italic}

newcommanddxdy[2]{; symup{d}{#1} , symup{d}{#2}}
newcommand{xzero}{symbfit{x}_{symbfup 0}}
newcommand{yzero}{symbfit{y}_{symbfup 0}}

begin{document}
begin{minipage}{20em}
The quick brown fox jumps over the lazy dog.  If it jumps with upward velocity
(symbfit{v}) at altitude (yzero), its height at time t is given by
[ gamma(t) = iint_0^t -symbfit{g} dxdy{t}{t} =
   - frac{symbfit{g} t^2}{2} + symbfit{v} t + yzero ]

The dog, being lazy, wants to look at the fox with minimal effort.  It should
rotate its head to an angle of

[ begin{cases}
     frac{muppi}{2}
       & mbox{if (symupDeltasymbf{x} t = xzero)} \
     tan^{-1} left( frac{gamma(t)}{symupDeltasymbf{x} t - xzero } right)
       & mbox{otherwise}
   end{cases} ]

end{minipage}
end{document}

documentclass{article}
usepackage[T1]{fontenc}
usepackage{textcomp}
usepackage{winfonts}
usepackage[utf8]{inputenc} % The default since 2018
usepackage{microtype}
usepackage{lipsum}

begin{document}
fontfamily{georgia}selectfont
lipsum
end{document}