auto str = "
class MyClass
{
    this(int a, float b)
    {
    }
}";

// One way
ldc.Class cls = executionEngine.getClassByName("MyClass");

auto ctor = cls.getConstructor!(function(int, float))();
Object instance = ctor(1, 3.14);

// Another way
Object instance = cls.instantiate([Variant(1), Variant(3.14)]);