Steroidsupply

ACP-196 For Treatment of Cancer CAS:1420477-60-6 WhatsApp:+8

May 31st, 2018
135
0
Never
Not a member of Pastebin yet? Sign Up, it unlocks many cool features!
text 0.64 KB | None | 0 0
  1. ACP-196 For Treatment of Cancer CAS:1420477-60-6 WhatsApp:+8618873306038
  2.  
  3.  
  4.  
  5. Name:ACP-196
  6. MF:C26H23N7O2
  7. CAS:1420477-60-6
  8. Molecular Weight:465.51
  9. Formula:C26H23N7O2
  10. CAS No.:1420477-60-6
  11. Storage:3 years -20°C powder
  12. Synonyms:N/A
  13.  
  14.  
  15. Description
  16. Acalabrutinib(ACP-196) is a selective second-generation Bruton's tyrosine kinase (BTK) inhibitor, which prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. ACP-196 has improved target specificity over ibrutinib with 323-, 94-, 19- and 9-fold selectivity over the other TEC kinase family members (ITK, TXK, BMX, and TEC, respectively) and no activity against EGFR.
Advertisement
Add Comment
Please, Sign In to add comment