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- ACP-196 For Treatment of Cancer CAS:1420477-60-6 WhatsApp:+8618873306038
- Name:ACP-196
- MF:C26H23N7O2
- CAS:1420477-60-6
- Molecular Weight:465.51
- Formula:C26H23N7O2
- CAS No.:1420477-60-6
- Storage:3 years -20°C powder
- Synonyms:N/A
- Description
- Acalabrutinib(ACP-196) is a selective second-generation Bruton's tyrosine kinase (BTK) inhibitor, which prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. ACP-196 has improved target specificity over ibrutinib with 323-, 94-, 19- and 9-fold selectivity over the other TEC kinase family members (ITK, TXK, BMX, and TEC, respectively) and no activity against EGFR.
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