In 1961, Eisenhower became the first U.S. president to be constitutionally prevented from running for re-election to the office, having served the maximum two terms allowed by the 22nd Amendment to the U.S. Constitution. The amendment was ratified in 1951, during Harry S. Truman's term, but it stipulated that Truman would not be affected by the amendment.

Eisenhower was also the first outgoing President to come under the protection of the Former Presidents Act; two then-living former Presidents, Herbert Hoover and Harry S. Truman, left office before the Act was passed. Under the act, Eisenhower was entitled to receive a lifetime pension, state-provided staff and a Secret Service detail