CREATE FUNCTION [dbo].[fn_SplitList]
(
    @RowData varchar(8000),
    @SplitOn varchar(5)
)
RETURNS @RtnValue table
(
    Id int identity(1,1),
    Data varchar(100)
)
AS
BEGIN
    Declare @Cnt int
    Set @Cnt = 1

    While (Charindex(@SplitOn,@RowData)>0)
    Begin
	    Insert Into @RtnValue (data)
	    Select
		    Data = ltrim(rtrim(Substring(@RowData,1,Charindex(@SplitOn,@RowData)-1)))

	    Set @RowData = Substring(@RowData,Charindex(@SplitOn,@RowData)+1,len(@RowData))
	    Set @Cnt = @Cnt + 1
    End

    Insert Into @RtnValue (data)
    Select Data = ltrim(rtrim(@RowData))

    Return
END

declare @table1 table(id int primary key
                     ,words varchar(max))
declare @id int
declare @words varchar(max)

insert into @table1 values(0, 'word1, word2, , word3, word4')
insert into @table1 values(1, 'word1, word2, word3, ,')
insert into @table1 values(2, 'word1,,,, ; word2')
insert into @table1 values(3, ';word1 word2, word3')

declare updateCursor cursor for
select id
      ,words
  from @table1

open updateCursor
fetch next from updateCursor into @id, @words
while @@fetch_status = 0
begin
  declare @row varchar(255)

  select @row = coalesce(@row+', ', '') + data
    from dbo.fn_SplitList(@words, ',')
  order by id desc

  update @table1
     set words = @row
   where id = @id

  fetch next from updateCursor into @id, @words
end
close updateCursor
deallocate updateCursor

select *
  from @table1

update t_desc set name =
(select name
from
(select name,
case when wb is null then rname when wb >= we then stuff(rname, wb, 128, REVERSE        (substring(rname, wb, 128))) else
stuff(rname, wb, we-wb+1, REVERSE(substring(rname, wb, we-wb+1))) end rname,
case when wb is null or wb > we then null else PATINDEX('%[a-z0-9]%', SUBSTRING(rname, we+1, 128))+we end wb,
case when we is null or wb > we then null else PATINDEX('%[a-z0-9][^a-z0-9]%', SUBSTRING(rname, we+1, 128))+we end we
from
(select name,
case when wb is null then rname when wb >= we then stuff(rname, wb, 128, REVERSE    (substring(rname, wb, 128))) else
stuff(rname, wb, we-wb+1, REVERSE(substring(rname, wb, we-wb+1))) end rname,
case when wb is null or wb > we then null else PATINDEX('%[a-z0-9]%', SUBSTRING    (rname, we+1, 128))+we end wb,
case when we is null or wb > we then null else PATINDEX('%[a-z0-9][^a-z0-9]%',     SUBSTRING(rname, we+1, 128))+we end we
from
(select name,
case when wb is null then rname when wb >= we then stuff(rname, wb, 128, REVERSE        (substring(rname, wb, 128))) else
stuff(rname, wb, we-wb+1, REVERSE(substring(rname, wb, we-wb+1))) end rname,
case when wb is null or wb > we then null else PATINDEX('%[a-z0-9]%', SUBSTRING        (rname, we+1, 128))+we end wb,
case when we is null or wb > we then null else PATINDEX('%[a-z0-9][^a-z0-9]%',         SUBSTRING(rname, we+1, 128))+we end we
from
(select name,
stuff(rname, wb, we-wb+1, REVERSE(substring(rname, wb, we-wb+1))) rname,
PATINDEX('%[a-z0-9]%', SUBSTRING(rname, we+1, 128))+we wb,
PATINDEX('%[a-z0-9][^a-z0-9]%', SUBSTRING(rname, we+1, 128))+we we
from
(select name, rname,
PATINDEX('%[a-z0-9]%', rname) wb,
PATINDEX('%[a-z0-9][^a-z0-9]%', rname) we
  from
(select t_desc.name, REVERSE(name) rname) t1) t2) t3) t4) t5) t6)