$file_type = explode('.', $image)[1];
$data = file_get_contents($image);
$path = 'public://images/';

if (file_prepare_directory($path, FILE_CREATE_DIRECTORY)) {

  $file = file_save_data($data, $path . md5($image) . '.' . $file_type, FILE_EXISTS_REPLACE);

  $node = Node::create(array(
    'type' => 'image',
    'title' => $image,
    'field_image' => array(
      'target_id' => $file->id(),
    ),
  ));
  $node->save();

}

$original_image = 'public://images/image.jpg';

// Load the image style configuration entity.
use DrupalimageEntityImageStyle;
$style = ImageStyle::load('max_2600x2600');

$uri = $style->buildUri($original_image);
$url = $style->buildUrl($original_image);

use DrupalfileEntityFile;
      use DrupalimageEntityImageStyle;
      use DrupalnodeEntityNode;

      $fileName = 'example.jpg';
      $destination =  "public://images/" . $fileName;
      $temporaryFile = 'temporary://' . $fileName;
      file_save_data($photoData, $temporaryFile, FILE_EXISTS_REPLACE);

      $style = ImageStyle::load('thumbnail');
      $style->createDerivative($temporaryFile, $destination);

      $file = File::create([
        'uid' => 1,
        'filename' => $fileName,
        'uri' => $destination,
        'status' => 1,
      ]);
      $file->save();

      if ($file) {
          $node->get('field_photos')->appendItem([
              'target_id' => $file->id(),
              'alt' => 'Alt text goes here',
          ]);
      }

      ...

      $node->save();