Debunking the lipid hypothesis

Egg consumption improves lipid profile, blood pressure, and reduces risk for cardiovascular mortality and diabetes.
http://www.ncbi.nlm.nih.gov/pubmed/20683785
http://www.ncbi.nlm.nih.gov/pubmed/11023005
http://www.ncbi.nlm.nih.gov/pubmed/18991244
http://www.ncbi.nlm.nih.gov/pubmed/21776466
http://www.ncbi.nlm.nih.gov/pubmed/19369056
http://www.ncbi.nlm.nih.gov/pubmed/21134328
http://www.ncbi.nlm.nih.gov/pubmed/15164336
http://www.ncbi.nlm.nih.gov/pubmed/18203890
http://www.ncbi.nlm.nih.gov/pubmed/17531457
http://www.ncbi.nlm.nih.gov/pubmed/16340654

"A meta-analysis of prospective epidemiologic studies showed that there is no significant evidence for concluding that dietary saturated fat is associated with an increased risk of CHD or CVD. More data are needed to elucidate whether CVD risks are likely to be influenced by the specific nutrients used to replace saturated fat."
http://www.ncbi.nlm.nih.gov/pubmed/20071648
http://ajcn.nutrition.org/content/early/2010/01/13/ajcn.2009.27725.abstract

Recommendations of the American Heart Association from 1982 are based on misinterpretation, obsolete science, and arbitrary choices without explanation.
http://www.ncbi.nlm.nih.gov/pubmed/6383010
http://highsteaks.com/a-critical-look-at-the-american-heart-associations-dietary-guidelines-from-1982/

"The mainstream hypothesis that LDL cholesterol drives atherosclerosis may have been falsified by non-invasive imaging of coronary artery plaque burden and progression."
http://www.ncbi.nlm.nih.gov/pubmed/19560285

"Cholesterol does not cause coronary heart disease in contrast to stress."
http://www.ncbi.nlm.nih.gov/pubmed/18609060

"The fallacies of the lipid hypothesis."
http://www.ncbi.nlm.nih.gov/pubmed/18615352

Low cholesterol is a risk factor for in-hospital mortality
http://www.ncbi.nlm.nih.gov/pubmed/12967690
http://www.ncbi.nlm.nih.gov/pubmed/19033015
http://www.clinchem.org/content/46/8/1114.full.pdf
http://ccforum.com/content/pdf/cc10584.pdf

"Dietary cholesterol reduces circulating levels of small, dense LDL particles, a well-defined risk factor for CHD."
http://www.ncbi.nlm.nih.gov/pubmed/20683785

"Public health emphasis on reducing SFA consumption without considering the replacement nutrient or, more importantly, the many other food-based risk factors for cardiometabolic disease is unlikely to produce substantial intended benefits."
http://www.ncbi.nlm.nih.gov/pubmed/20354806

Amyotrophic lateral sclerosis patients with elevated LDL/HDL ratio survive by more than 12 months longer.
http://www.ncbi.nlm.nih.gov/pubmed/18199832

"We conclude that major weight loss was associated with a late rise in serum cholesterol, possibly from mobilization of adipose cholesterol stores, which resolved when weight loss ceased."
http://www.ncbi.nlm.nih.gov/pubmed/2035468

"The results show that dietary and plasma saturated fat are not related, and that increasing dietary carbohydrate across a range of intakes promotes incremental increases in plasma palmitoleic acid, a biomarker consistently associated with adverse health outcomes."
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0113605

Replacing saturated fat with carbohydrates increases small, dense LDL particles, shifts to an overall atherogenic lipid profile, and increases incidence of diabetes and obesity. Replacing saturated fat with omega 6 polyunsaturated fats increases risk of cancer, increases risk of coronary heart disease, cardiovascular events, and death to heart disease and overall mortality, increases oxidized LDL-C, reduces HDL-C.
http://openheart.bmj.com/content/1/1/e000032.full

Low cholesterol is associated with mortality from cardiovascular disease.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247776/

Conclusion: The lipid hypothesis is foolish.