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Raw Pharmaceutical Loperamide Hydrochloride/Loperamide HCl

Mar 2nd, 2018
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  1. Raw Pharmaceutical Loperamide Hydrochloride/Loperamide HCl For Antidiarrheal CAS 34552-83-5
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  9. Loperamide hydrochloride Description:
  10. Loperamide hydrochloride is a white or almost white crystalline powder, can be used as antidiarrheal, or long-acting anti-diarrhea drugs used for the treatment of acute and chronic dysentery.
  11. Loperamide slows the rhythm of digestion so that the small intestines havemore time to absorb fluid and nutrients from the foods you eat.
  12. Loperamide is effective for the treatment of a number of types of diarrhea. This includes control of acute nonspecific diarrhea, mild traveler's diarrhea, irritable bowel syndrome, chronic diarrhea due to bowel resection, and chronic diarrhea secondary to inflammatory bowel disease. It is also useful for reducing ileostomy output. Off Label uses for loperamide also include chemotherapy induced diarrhea, especially related toirinotecan use.
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  14. Product Name: Loperamide hydrochloride
  15. Synonyms: LABOTEST-BB LT00134703;LOSERAMIN;LOPERAMIDE HCL;LOPERAMIDE HYDROCHLORIDE;4-(4-CHLOROPHENYL)-4-HYDROXY-N,N-DIMETHYL-ALPHA,ALPHA-DIPHENYL-1-PIPERIDINBUTYRAMIDE HYDROCHLORIDE;4-(4-CHLOROPHENYL)-4-HYDROXY-N,N-DIMETHYL-ALPHA,ALPHA-DIPHENYL-1-PIPERIDINEBUTANAMIDE HYDROCHLORIDE;4-(4-chlorophenyl)-4-hydroxy-n,n-dimethyl-alpha,alpha-diphenylpiperidine-1-butyramide monohydrochloride;4-[P-CHLOROPHENYL]-4-HYDROXY-N,N-DIMETHYL-ALPHA,ALPHA-DIPHENYL-1-PIPERIDINEBUTYRAMIDE HYDROCHLORIDE
  16. CAS: 34552-83-5
  17. MF: C29H34Cl2N2O2
  18. MW: 513.5
  19. EINECS: 252-082-4
  20. Product Categories: ACTIVE PHARMACEUTICAL INGREDIENTS;Intermediates & Fine Chemicals;Pharmaceuticals;Isotope Labeled Compounds;Opioid receptor and opioid-like receptor;Amines;Heterocycles;IMODIUM;Other APIs
  21. MP 223-225°C
  22. Appearance White Solid
  23. storage temp. Store at RT
  24. Merck 5571
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  26. Safety Information:
  27. Hazard Codes T
  28. Risk Statements 25
  29. Safety Statements 45
  30. RIDADR UN 2811 6.1/PG 3
  31. WGK Germany 3
  32. RTECS TM4960000
  33. HazardClass 6.1(b)
  34. PackingGroup III
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  36. Usage And Synthesis:
  37. 1.Labeled Loperamide, which is used as an antidiarrheal
  38. 2.Ca channel blocker
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  41. Function:
  42. For acute diarrhea and chronic diarrhea caused by a variety of reasons.
  43. Is effective to diarrhea caused stomach, intestinal partial resection and hyperthyroidism .
  44. Particularly applicable to chronic functional diarrhea that other antidiarrheal effect is not significant.
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  46. Applications:
  47. Loperamide acts on receptors along the small intestine to decrease circular and longitudinal muscle activity. Loperamide exerts its antidiarrheal action by slowing intestinal transit and increasing contact time, and perhaps also by directly inhibiting fluid and electrolyte secretion and/or stimulating salt and water absorption.
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