String Body = 'notice='+ EncodingUtil.base64Encode(blob.valueof(Payload));


            HttpRequest Publishreq = new HttpRequest();
            Publishreq.setHeader('Authorization',Token);
            Publishreq.setHeader('Accept','application/json');
            Publishreq.setBody(Body);
            Publishreq.setmethod('POST');

            Publishreq.setEndpoint( 'https://endpoint.com/api/qualification/latest/notice/submit');//+Body);

            HTTP Publish = new HTTP();
            HTTPResponse PublishResponse =new HttpResponse();

            PublishResponse = Publish.send(Publishreq);

curl -X POST -F notice=SomeBase64XML -H "Authorization: Basic SomeBase64Credential" https://endpoint.com/api/qualification/latest/notice/submit