<div class="myclass">
  <span>...</span>
  <div>
       <table>
              <colgroup>...</>
              <tbody>
                    <tr>...</tr>
                    <tr>
                         <td>
                              <input ...name="myname" ...>
                         </td>
                    </tr>
                    <tr>...</tr>
              <tbody>
       </table>
  </div>

</div>

.//div[@class="myclass"][.//input[@name="myname"]]

//input[@name='myname']/ancestor::div[@class = 'myclass']

//input[@name='myname']/ancestor::div[contains(@class,'myclass')]

self::*/ancestor::div[contains(@class,'myclass')]

grandparent = element.find_element_by_xpath('../..')