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https://www.lowes.com/pd/Crown-128-fl-oz-Fast-to-Dissolve-Methyl-Ethyl-Ketone-MEK/3024048Synthesis of Benzene

	Required chems:
	2000g Sodium Benzoate - $30 - $30/batch
	1200g Sodium Hydroxide - $15 - $15/batch

	Total: $ 45

1. Crush Sodium Benzoate and Sodium Hydroxide in a mortar/pestle, and mix then together

2. Add powder to a flask set for distillation

3. Add crude benzne to a separatory funnel, and wash multiple times with 25ml water, then capped, shaken, and vented

4. Add benzene to a flask containing Calcium Chloride. Mix and allow to sit for 2 hours.

5. Set up for distillation up to 80C

Yield: 860ml Anhydrous Benzene




Synthesis of Anhydrous Aluminium Chloride

	Required chems:
	640g Zinc Chloride - $30 - $30/batch
	104g Aluminium Powder - $10 - $10/batch

	Total: $40

1. Be careful to avoid atmospheric moisture in all steps through this reaction

2. Mix 640g Zinc Chloride and 104g Aluminium Powder in a large flask

3. Connect the flask to a distillation flask, downward at a steep angle

4. Use a bottle that can be fully sealed for the end, and wrap in cold packs

5. Heat flask until all smoke is gone

Yield: 224g Anhydrous Aluminium Chloride




Synthesis of Propiophenone

	Required chems:
	350ml Benzene
	224g Anhydrous Aluminum Chloride
	133g Phosporus Pentoxide - $167 - $150/batch
	105g Propionic Acid - $57 - $12/batch
	70ml 36% Hydrochloric Acid

	Total: $206

1. Add 50ml Benzene to a flask on a hot plate, with a sitter

2. Start stirring, and slowly add Anhydrous Aluminium Chloride

3. Slowly add Phosphorus Pentoxide, and add a condenser and drying tube to flask

4. Remove drying tube, and very slowly add 15g Propionic Acid

5. Heat the mixutre to keep at reflux, and add drying tube

6. Leave mixture stirring/refluxing for 1 hours, then stir manually for a few seconds

7. Leave mixture refluxing for another hour

8. Allow to cool down, then add 100ml cold water slowly

9. Add 10ml Hydrochloric Acid

10. Allow to cool, then add to a separating funnel

11. Discard bottom layer, and add top layer to a flask

12. Set up for distillation to 160C

Yield: 56.7g Propiophenone




Synthesis of Chloroform

	Required chems:
	2500g Calcium Hypochlorite - $90 - $90/batch
	1100ml Acetone - $5 - $5/batch

	Total - $21

1. Place 100g Calcium Hypochlorite in a mortar, and add 6250ml water by drops

2. Add the mixture to a 1L flask fit with a condenser, in an ice bath.

3. Add 1100ml acetone by drops and shake.

4. Heat the flask in a boiling water bath for 5-10 min, then cool in water.

5. Fit flask with delivery-tube, and reverse the water condenser for distallation.

6. Heat flask in a water bath until distillation is complete.

7. Shake acidic chloroform with dilute sodium hyroxide in a separating funnel.

8. Place lower layer in a flask, and dry over calcium chloride for 15-20 min.

9. Filter into a distilling flask fitted with a water-condenser.

10. Distill chloroform.

Yield: 500ml




Synthesis of Methylamine Hydrochloride

	Required chems:
	1100g Ammonium Chloride - $16 - $8/batch
	2L 35-40% Formaldehyde - $150 - $75/batch
	.5L Chloroform

	Total - $160

1. Pour formaldehyde in a 5L flask with ammonium chloride

2. Heat slowly to 90C, stirring occasionally

3. Put in ice bath to keep temp under 104C

4. After reaction slows, heat flask to keep at 104C for 3-4 hours

5. Turn heat up to boil away water until ammonium chloride comes out of solution

6. Cool to 20C and vacuum filter

7. Transfer to smaller flask and boil until internal temp reaches 160C

8. Turn on vacuum and allow to cool then heat up to 160C

9. Turn of vacuum and heat, and pour into smaller beaker to allow solidification

10. Wash multiple times with chloroform until it's a white mush

11. Vacuum filter and let dry

Yield: 400g Methylamine Hydrochloride




Synthesis of Bromine

	Required chems
	60ml 16% Muriatic Acid
	72g TCCA - $7 - $3/batch
	400ml 35% Sodium Bromide - $7 - $7/batch

	Total: $27

1. Set up for simple distillation, with receiving flask in a ice bath

2. Add 72g crushed TCCA to the flask

3. Add 60ml 16% Muratic acid to an addition flask

4. Add 400ml 35% Sodium Bromide to the flask

5. Stir strongly, and add Muratic acid dropwise

6. Heat the mixture to 100C until it clears of Bromine vapors

7. Put into separatory funnel, and drain lower Bromine layer into another separatory funnel

8. Add 20ml Sulfuric Acid slowly, then cap and shake

9. Drain lower bromine layer into a flask

Yield: 109g Bromine




Synthesis of Ephedrone

	Required chems:
	56.5g Propiophenone
	130ml Benzene
	67.5g Bromine
	20% Sodium Carboante Solution
	56.5g Methylamine Hydrochloride
	67.5g Caustic Soda - $15 - $1/batch
	5% Hydrochloric Acid
	1N Hydrochloric Acid
	Acetone

	Total - $15

1. Add 56.5g Propiophenone and 130ml Benzene to a flask fitted with a stirrer, dropping funnel, thermometer, and air inlet tube

2. 67.5g Bromine is added at 30C at such a rate that the Bromine became decolorized.

3. If the decolorization of the reaction mixture was slow, air is blown through it to remove formed Hydrogen Bromide

4. Stir for 30 minutes, and blow out Hydrogen Bromide

5. Add 30ml water, stir thoroughly

6. Add 20% Sodium Carbonate Solution until mixture is weakly alkaline to litmus.

7. Add a solution of 56.5g Methylamine Hydrochloride in 55ml water

8. Add a solution of 67.5g Caustic Soda in 80ml water over 10 minutes at 50-60C

9. Raise temp to 70C, then cool to room temperature

10. Unconverted Methylamine is blown into absorption flasks cibtaububg 5% Hydrochloric Acid.

11. Seperate Benzene and Aqueous Alkaline layers, and the latter extracted twice with benzene.

12. Add extracts to main solution

13. Wash solution with water, and stir with 1N Hydrochloric Acid Solution

14. Resultant aqueous solution of Ephedrone Hydrochloride is evaporated under vacuum to a thick syrup

15. Syrup is stirred with acetone to yield a white precipitate of Ephedrone Hydrochloride.

16. Percipitate is heated to boiling with acetone, then cooled.

17. White crystals are filtered off, washed with acetone, and dried.

18. Less pure Ephedrone Hydrochloride is obtained from the mother liquors and crystallized from a mixture of ethyl alchohol and acetone.

19. Methylamine Hydrochloride collected in absorption flask is evaporated to dryness, recovering 21g/

Yield: 62g Ephedrone Hydrochloride




Synthesis of Hydrogen

	Required chems:
	Aluminium Foil
	Concentrated aqueous Sodium Hydroxide

	Total: $0

1. Add aluminum foil and Sodium Hydroxide solution to a flask, passed through an ice chilled flask

Yield: ?




Synthesis of Ephedrine Hydrochloride

	Required chems:
	62g Ephedrone Hydrochloride
	14.2g Caustic Soda
	135ml Ethyl Alchohol - $15 - $5/batch
	Molecular Hydrogen
	Raney Nickel Catalyst - $50 - $10/batch
	Hydrogen Chloride - $30 - $10/batch

	Total - $145

1. Add a solution of 14.2g Caustic Soda in 134ml Ethyl Alchohol to a solution of 62g Eoheddrone Hydrochloride

2. Percipitated Sodium Chloride is filtered off and washed with alchohol, then added to the main alchoholic solution of ephedrine base.

3. Reduce by molecular Hydrogen in presence of Raney Nickel Catalyst

4. Solution is cooled to 5-10C, and the catalyst is filtered off.

5. Solution is acidified with a solution of Hydrogen CHloride in alchohol.

6. Precipitate Sodium Chloride is filtered off, and the filtreate is evaporated under vacuum at less than 45C.

Yield: 40g DL-Ephedrine Hydrochloride.




Synthesis of Phenylacetone (P2P)

	Required chems:
	341g 75% Sulfuric Acid - $30 - $6/batch
	.3g ZnCl2 - $15 - $.5/batch
	64g Ephedrine
	Toluene - $15 - $15/batch

	Total: $60

1. Mix 341g 75% Sulfuric Acid with 1g ZnCl2.

2. Dissolve 64g Ephedrine at a tempurature of 50-100C

3. At 125C, steam is bassed through the solution

4. At 145C, the stream of steam is increased

5. Keep heating and steam distilling for 3 hours

6. Cool down, and isolate the P2P by a toluene extract

7. Distill through through a short vigreaux column

Yield: 43.3g Phenylacetone



Synthesis of Racemic Amphetamine

	Required chems:
	40g Phenylacetone
	200mg Ethanol
	200ml 25% Ammonia - $35 - $7/batch
	40g AL-grit
	.3g HgCl2 - $35 - $2/batch
	120g KOH - $15 - $2/batch
	Ether - $36 - $2/batch
	20% HCl - $30 - $2/batch
	Na2SO4 - $13 - $2/batch

	Total: $209

1. Mix 40g P2P, 200ml Ethanol, 200ml 25% Ammonia, 40g AL-grit, .3g HgCl2

2. Warm with vigorous stirring until a reaction takes place, then stop warming

3. If the reaction becomes too violent, place in ice bath

4. When the reaction has settled, reflux with vigorous stirring for 2 hours.

5. Concentrate in a vacuum to 200ml, then pour into ice water.

6. Alkanize with 120g KOH, then extract with ether.

7. Treat extracts with 20% HCl

8. The resulting water layer is extracted with 150ml ether

9. The organic layer is dried over Na2SO4, the ether evaporated, and the residue distilled in vacuum.

Yield: 12.5g

Grand total: $888 =  $500/batch = $40/gram