sessions = sessions.Where(y => y.session.SESSION_DIVISION.Any(x => x.DIVISION.ToUpper().Contains(SearchContent)) ||
                                                   y.session.ROOM.ToUpper().Contains(SearchContent) ||
                                                   y.session.COURSE.ToUpper().Contains(SearchContent));

if (!String.IsNullOrEmpty(Division)) {
    sessions = sessions.Where(y => y.session.SESSION_DIVISION.Any(x => x.DIVISION.ToUpper().Contains(SearchContent)));
}

if (!String.IsNullOrEmpty(Room)) {

    // this shoudl be OR
    sessions = sessions.Where(y => y.session.ROOM.ToUpper().Contains(SearchContent));
}

if (!String.IsNullOrEmpty(course)) {

    // this shoudl be OR
    sessions = sessions.Where(y => y.session.COURSE.ToUpper().Contains(SearchContent));
}

var queries = new List<IQueryable<Session>>();
if (!String.IsNullOrEmpty(Division)) {
    queries.Add(sessions.Where(y => y.session.SESSION_DIVISION.Any(x => x.DIVISION.ToUpper().Contains(SearchContent))));
}

if (!String.IsNullOrEmpty(Room)) {

    // this shoudl be OR
    queries.Add(sessions.Where(y => y.session.ROOM.ToUpper().Contains(SearchContent)));
}

if (!String.IsNullOrEmpty(course)) {

    // this shoudl be OR
    queries.Add(sessions.Where(y => y.session.COURSE.ToUpper().Contains(SearchContent)));
}

sessions = queries.Aggregate(sessions.Where(y => false), (q1, q2) => q1.Union(q2));