esomeprazole magnesium

introduction

name:  esomeprazole magnesium
cas number: 161973-10-0
formula: c34h36mgn6o6s2
molecular weight:  713.12
synonyms: magnesium,bis[5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1h-benzimidazolato]-,[t-4-(s),(s)]-;(-)-omeprazole magnesium; (s)-omeprazole magnesium; h 199/18; nexium; perprazole; raciper;
package:  1kg for aluminum bag, 25 kg for paper drum
appearance:  off-white powder
uses: s-form of omeparzole/ gastric proton-pump inhabitor
uses: antiulcerative

what is esomeprazole magnesium
esomeprazole sold under the brand name nexium among others, is a proton-pump inhibitor which reduces stomach acid. it is used in the treatment of dyspepsia, peptic ulcer disease,gastroesophageal reflux disease, and zollinger-ellison syndrome.
it decreases secretion of acid through inhibition of the h+/k+-atpase in the parietal cells of the stomach.by inhibiting the functioning of this transporter, the drug prevents formation of stomach acid.
esomeprazole is the (s)-(−)-enantiomer of omeprazole. esomeprazole is currently sold over the counter in the us and the uk.

application of esomeprazole magnesium

esomeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). it works by decreasing the amount of acid your stomach makes. it relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. this medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. esomeprazole belongs to a class of drugs known as proton pump inhibitors (ppis).
if you are self-treating with this medication, over-the-counter esomeprazole products are used to treat frequent heartburn (occurring 2 or more days a week). since it may take 1 to 4 days to have full effect, these products do not relieve heartburn right away.
the primary uses of esomeprazole are gastroesophageal reflux disease, treatment and maintenance of erosive esophagitis, treatment of duodenal ulcers caused by h. pylori, prevention of gastric ulcers in those on chronic nsaid therapy, and treatment of gastrointestinal ulcers associated with crohn's disease.

how to use esomeprazole magnesium

read the medication guide and the patient information leaflet if available from your pharmacist before you start taking esomeprazole and each time you get a refill. if you have any questions, ask your doctor or pharmacist.
take this medication by mouth as directed by your doctor, usually once daily, at least 1 hour before a meal. if you are self-treating, follow all directions on the product.

function

1. gastroesophageal reflux disease (gerd).

2. treatment of erosive reflux esophagitis.

3. patients who have been cured of esophagitis prevent recurrence of long-term maintenance.

4. the symptom control of gastroesophageal reflux disease (gerd) is combined with appropriate antimicrobial therapy to eradicate h. pylori.

5. healing of duodenal ulcers associated with helicobacter pylori infection.

6. prevent the recurrence of peptic ulcer associated with helicobacter pylori.

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