import pyodbc
driver = 'SQL Server'
server = '**server-name**'
db1 = 'CorpApps'
tcon = 'yes'
uname = 'jnichol3'
pword = '**my-password**'

cnxn = pyodbc.connect('DRIVER={SQL Server};SERVER=server;DATABASE=db1;UID=uname;PWD=pword;Trusted_Connection=yes')
cursor = cnxn.cursor()
cursor.execute("select * from appaudit_q32013")
rows = cursor.fetchall()
for row in rows:
    print row

Traceback (most recent call last):
  File "pyodbc_test.py", line 9, in <module>
    cnxn = pyodbc.connect('DRIVER={SQL Server};SERVER=server;DATABASE=db1;UID=uname;PWD=pword;Trusted_Connection=yes')
pyodbc.Error: ('08001', '[08001] [Microsoft][ODBC SQL Server Driver][DBNETLIB]SQL Server does not exist or access denied. (17) (SQLDriverConnect); [01000] [Microsoft][ODBC SQL Server Driver][DBNETLIB]ConnectionOpen (Connect()). (53)')

cnxn = pyodbc.connect(driver='{SQL Server}', host=server, database=db1,
                      trusted_connection=tcon, user=uname, password=pword)