Mango Peels :DD

Mango Peels
>Bioactive conserves were extracted using 80% acetone from peels of raw and ripe mango fruits and subjected to acid hydrolysis
>Prominent phenolic compounds identified: [Protocatechuic acid], Gentisic acid, and Gallic acid.
>Gallic acid, syringic acid, mangiferin, ellagic acid, gentisyl-protocatechuic acid, quercetin were the phenolic compounds identified in both raw and ripe peels, while raw peel showed the presence of glycosylated iriflophenone and maclurin derivatives also
>β-Carotene was the major carotenoid followed by violaxanthin and lutein.(https://www.sciencedirect.com/science/article/abs/pii/S0278691510005752)

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[Protocatechuic acid]
>PCA has a structural similarity with gallic acid, caffeic acid, vanillic acid, and syringic acid which are well-known antioxidant compounds. More than 500 plants contain PCA as active constituents imparting various pharmacological activity and these effects are due to their antioxidant activities, along with other possible mechanisms, such as anti-inflammatory properties and interaction with several enzymes.
>Roselle calyx (Hibiscus sabdariffa L.) extract and protocatechuic acid were both found to decrease {lipid oxidation} levels in ground beef tissue. Protocatechuic acid also exhibited dose-dependent effect.
>These data support that roselle calyx extract and protocatechuic acid may be used for muscle foods to prevent contamination from campylobacter and aerobes and delay lipid oxidation and also serve as a good food preservative.

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{Lipid Oxidation}
>One step in the cascade of Adriamycin nephrotoxicity, leading to metabolic alterations in the <epithelial cells>, which in turn could lead to structural alterations in the <glomerular filtration barrier>.(https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/lipid-oxidation)

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<Epithelial cells>
>They form the covering of all body surfaces, line body cavities and hollow organs, and are the major tissue in glands. They perform a variety of functions that include protection, secretion, absorption, excretion, filtration, diffusion, and sensory reception.(https://training.seer.cancer.gov/anatomy/cells_tissues_membranes/tissues/epithelial.html)

<Glomerular filtration barrier>
>The glomerular filtration barrier is a highly specialized blood filtration interface that displays a high conductance to small and midsized solutes in plasma but retains relative impermeability to macromolecules.(https://www.hindawi.com/journals/ijn/2012/749010/)

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