My /etc/apache2/httpd.conf looks like

<Location /sabnzbd>
order deny,allow
deny from all
allow from all
ProxyPass http://localhost:8080/sabnzbd
ProxyPassReverse http://localhost:8080/sabnzbd
</Location>

Alias /newznab /var/www/newznab/www
<Directory /var/www/newznab/www/>
            Options FollowSymLinks
            AllowOverride All
</Directory>

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And /var/www/newznab/www/.htaccess contains

RewriteEngine on
RewriteBase /newznab

# Do not process images or CSS files further
RewriteRule \.(css|jpe?g|gif|png|js|ico|mp3)$ - [L]

# Leave /admin and /install static
RewriteRule ^(admin|install).*$ - [L]

# Rewrite web pages to one master page
RewriteRule ^([^/\.]+)/?$ index.php?page=$1 [QSA,L]
RewriteRule ^([^/\.]+)/([^/]+)/?$ index.php?page=$1&id=$2 [QSA,L]
RewriteRule ^([^/\.]+)/([^/]+)/([^/]+)/? index.php?page=$1&id=$2&subpage=$3 [QSA,L]

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/etc/apache2/sites-available/newznab

<VirtualHost *:80>
    ServerAdmin webmaster@localhost
    ServerName media-server

    # These paths should be fine
    DocumentRoot /var/www/newznab/www
    ErrorLog /var/log/apache2/error.log
    LogLevel warn
</VirtualHost>


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/var/log/apache2/error.log

[Sun Dec 16 06:25:07 2012] [notice] Apache/2.2.16 (Debian) PHP/5.3.3-7+squeeze14 with Suhosin-Patch configured -- resuming normal operations
[Sun Dec 16 16:04:34 2012] [error] [client 192.168.1.65] File does not exist: /var/www/nnplus/install
[Sun Dec 16 16:31:28 2012] [notice] caught SIGTERM, shutting down
[Sun Dec 16 16:31:30 2012] [notice] Apache/2.2.16 (Debian) PHP/5.3.3-7+squeeze14 with Suhosin-Patch configured -- resuming normal operations
[Sun Dec 16 16:31:50 2012] [error] [client 192.168.1.65] File does not exist: /etc/apache2/htdocs
[Sun Dec 16 17:00:22 2012] [notice] caught SIGTERM, shutting down
[Sun Dec 16 17:00:24 2012] [notice] Apache/2.2.16 (Debian) PHP/5.3.3-7+squeeze14 with Suhosin-Patch configured -- resuming normal operations
[Sun Dec 16 17:00:45 2012] [error] [client 192.168.1.65] PHP Fatal error:  Allowed memory size of 262144 bytes exhausted (tried to allocate 523800 bytes) in Unknown on line 0
[Sun Dec 16 17:00:50 2012] [error] [client 192.168.1.65] PHP Fatal error:  Allowed memory size of 262144 bytes exhausted (tried to allocate 523800 bytes) in Unknown on line 0
[Sun Dec 16 17:07:09 2012] [notice] caught SIGTERM, shutting down
[Sun Dec 16 17:07:10 2012] [notice] Apache/2.2.16 (Debian) PHP/5.3.3-7+squeeze14 with Suhosin-Patch configured -- resuming normal operations
[Sun Dec 16 17:07:23 2012] [error] [client 192.168.1.65] PHP Fatal error:  Allowed memory size of 262144 bytes exhausted (tried to allocate 523800 bytes) in Unknown on line 0
[Sun Dec 16 17:07:28 2012] [error] [client 192.168.1.65] PHP Fatal error:  Allowed memory size of 262144 bytes exhausted (tried to allocate 523800 bytes) in Unknown on line 0