$HTTP["host"] == "/var/www/website" {
     url.rewrite-if-not-file = ("^/([a-zA-Z0-9_-]+)" => "/home.php?username=$1")
}

url.rewrite-if-not-file = ("^/(.*)$" => "/home.php?username=$1")

$HTTP["host"] == "/var/www/website" {
   url.rewrite-if-not-file = ("^/(.*)$" => "/home.php?username=$1")
}