documentclass[10pt,final,hyphenatedtitles]{article}

usepackage[latin]{babel}
usepackage{graphicx} % Demo for MWE

usepackage{flowfram}
usepackage{lipsum}
setlength{columnsep}{0.2cm}
setlength{columnwidth}{dimexpr textwidth-2columnsep}
setlength{columnwidth}{0.25columnwidth}

newstaticframe[1]{dimexpr 2columnwidth+columnsep}{0.28textheight}{0pt}{0.72textheight}[widecolumn]

newflowframe[1]{columnwidth}{0.70textheight}{0pt}{0pt}
newflowframe[1]{columnwidth}{0.70textheight}{dimexpr columnwidth+columnsep}{0pt}
newflowframe[1]{columnwidth}{textheight}{dimexpr 2columnwidth+2columnsep}{0pt}
newflowframe[1]{columnwidth}{textheight}{dimexpr 3columnwidth+3columnsep}{0pt}

begin{document}

sloppy% default for multicols
begin{staticcontents*}{widecolumn}
lipsum[10]
end{staticcontents*}

lipsum[1-2]
end{document}