import os
import errno

def mkdirs(path):
    try:
        os.makedirs(path)
    except OSError as exc:
        if exc.errno == errno.EEXIST and os.path.isdir(path):
            pass
        else:
            raise

if __name__ == '__main__':
    home = os.path.expanduser("~")
    mkdirs(home+'/first/second/third')