Linux Bowser 4.1.10-1-vfio-lts #1 SMP PREEMPT Thu Oct 8 12:38:10 CEST 2015 x86_64 GNU/Linux
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win 10 pro x64 with gtx 680. Bunch of Errors and Code 43 for the GPU
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#!/bin/bash

sudo qemu-system-x86_64 -enable-kvm -machine pc -cpu host,kvm=off \
-smp 4,sockets=1,cores=2,threads=2  \
-vga none \
-device vfio-pci,host=05:00.0,addr=1f.0,x-pci-device-id=4480,x-vga=on,multifunction=on \
-device vfio-pci,host=05:00.1,addr=1f.1 \
-device vfio-pci,host=00:1b.0,addr=0f.0 \
-name Windows-10 \
-m 2G \
-boot d \
-cdrom /vm/win10.iso \
-drive file=/vm/ram.img,format=raw \
-usbdevice host:046d:c52b \
-usbdevice host:045e:0291 \
-monitor stdio -s


exit 0

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OS X Yosemite 10.10.5 with 9600GT. Everything works perfectly fine
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#!/bin/bash


sudo qemu-system-x86_64 -enable-kvm -M q35 -m 14096 -cpu core2duo,hv_time,hv_relaxed,hv_vapic,hv_spinlocks=0x1fff \
-smp 8,sockets=2,cores=2,threads=2 \
-device ioh3420,bus=pcie.0,addr=1c.0,multifunction=on,port=1,chassis=1,id=root.1 \
-device vfio-pci,host=04:00.0,bus=root.1,addr=00.0,multifunction=on,x-vga=on,romfile=/vm/9600GT.rom \
-boot d \
-drive file=/vm/Clover.iso,if=ide,index=5,media=cdrom \
-hdc /vm/storage.img \
-hda /vm/osxII.img \
-netdev user,id=net0 \
-device e1000-82545em,netdev=net0,mac=DE:AD:BE:EF:AD:3c \
-vga none \
-usb -device usb-host,hostbus=$(lsusb | grep 05ac:0221 | cut -f 2 -d " "),hostaddr=$(lsusb | grep 05ac:0221 | cut -f 4 -d " " | cut -c 1-3) \
-usb -device usb-host,hostbus=$(lsusb | grep 0a12:0001 | cut -f 2 -d " "),hostaddr=$(lsusb | grep 0a12:0001 | cut -f 4 -d " " | cut -c 1-3) \
-monitor stdio -vnc :2

exit 0