public class MainActivity extends Activity {

public static final int REQUIRED_PERMISSIONS = 001;

@Override
public void onCreate(Bundle savedInstanceState) {
    super.onCreate(savedInstanceState);
    setContentView(R.layout.activity_main);
    setRequestedOrientation(ActivityInfo.SCREEN_ORIENTATION_PORTRAIT);

    //give here permissions what ever you want...

    if CheckPermission(this, Manifest.permission.CAMERA)

    {
        PermHandling();
    }

    //now reqest runtime permissions..

    else {
        RequestPermission(MainActivity.this, Manifest.permission.CAMERA, REQUIRED_PERMISSIONS);
    }

}
private void PermHandling() {
    //Your app internal parts....
    //Here your stuff works...
}

//private void NewPermHandling(){

//}

@Override
public void onRequestPermissionsResult(int permsRequestCode, String[] permissions, int[] grantResults) {

    switch (permsRequestCode) {

        case REQUIRED_PERMISSIONS: {
            if (grantResults.length > 0
                    && grantResults[0] == PackageManager.PERMISSION_GRANTED) {
                PermHandling();
            } else {
                //Toast.makeText(this, "Please Grant Permissions other wise app will close.!", Toast.LENGTH_SHORT).show();

                /*AlertDialog.Builder builder = new AlertDialog.Builder(MainActivity.this);
                   builder.setMessage("Note: Please Grant Permissions");
                   builder.setTitle("Grant Permissions Again");
                   builder.setPositiveButton("OK",null);

                 builder.setPositiveButton("OK", new DialogInterface.OnClickListener() {
                @Override
                public void onClick(DialogInterface dialog, int which) {

                dialog.dismiss();
                Intent la = new Intent(Qdata.this, AQdata.class);
                startActivity(la);
                finish();
                }
                });
               AlertDialog dialog = builder.create();
               dialog.show();*/

            }
            return;
        }
    }
}

public void RequestPermission(Activity thisActivity, String Permission, int Code) {
    if (ContextCompat.checkSelfPermission(thisActivity,
            Permission)
            != PackageManager.PERMISSION_GRANTED) {
        if (ActivityCompat.shouldShowRequestPermissionRationale(thisActivity,
                Permission)) {
        } else {
            ActivityCompat.requestPermissions(thisActivity,
                    new String[]{Permission},
                    Code);
        }
    }
}

public boolean CheckPermission(Context context, String Permission) {
    if (ContextCompat.checkSelfPermission(context,
            Permission) == PackageManager.PERMISSION_GRANTED) {
        return true;
    } else {
        return false;
    }
}