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WebClient webClient = new WebClient();
// Register the callback
webClient.DownloadStringCompleted += new DownloadStringCompletedEventHandler(webClient_DownloadStringCompleted);
webClient.DownloadStringAsync(new System.Uri(YOUR_URL));

void webClient_DownloadStringCompleted(object sender, DownloadStringCompletedEventArgs e)
{
    if (e.Error == null)
    {
        updateSomething(e.result);
    }
}