if (Request.UserAgent.Contains("AppleWebKit"))
{
    Request.Browser.Adapters.Clear();
}

if (Request.UserAgent.Contains("Safari"))
{
    Page.ClientTarget = "uplevel";
}

Mozilla/5.0 (Windows; U; Windows NT 5.1; en-US) AppleWebKit/525.13 (KHTML, like Gecko) Chrome/0.X.Y.Z Safari/525.13.