Tweaks to be ran from the cmd line
[ Only for Windows with 6.x kernel (Windows Vista, 7, 2008) ]:

netsh int tcp set heuristics disabled
netsh int tcp set global autotuninglevel=disabled
netsh int tcp set global congestionprovider=ctcp
netsh int tcp set global rss=enabled
netsh int tcp set global chimney=enabled
netsh int tcp set global dca=enabled
netsh int tcp set global netdma=enabled

Tweaks to be placed in a registry file and then added to system registry
[ For 5.x (XP, 2003) and 6.x ]:

REGEDIT4
[HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Services\Tcpip\Parameters]
"MaxUserPort"=dword:0000fffe
"TcpTimedWaitDelay"=dword:0000001e
"StrictTimeWaitSeqCheck"=dword:00000001
"DefaultTTL"=dword:00000040
"EnableTCPA"=dword:00000001
"Tcp1323Opts"=dword:00000001
"TCPMaxDataRetransmissions"=dword:00000007
"SynAttackProtect"=dword:00000001
[HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Services\Tcpip\ServiceProvider]
"LocalPriority"=dword:00000004
"HostsPriority"=dword:00000005
"DnsPriority"=dword:00000006
"NetbtPriority"=dword:00000007
[HKEY_LOCAL_MACHINE\SOFTWARE\Policies\Microsoft\Windows\Psched]
"NonBestEffortLimit"=dword:00000000