Gzip

from __future__ import print_function
import gzip
import io
import subprocess


def regular():
    i = 0
    with gzip.open("human_g1k_v37.fasta.gz") as f:
        for line in f:
            i += 1
    print(i)


def buffered_gzip():
    i = 0
    gz_file = gzip.open("human_g1k_v37.fasta.gz")
    gz_file.read1 = gz_file.read
    with io.TextIOWrapper(gz_file) as f:
        for line in f:
            i += 1
    print(i)


def zcat()
    i = 0
    p = subprocess.Popen(
        ["gzcat", "human_g1k_v37.fasta.gz"],
        stdout=subprocess.PIPE
    )

    for line in p.stdout:
        i += 1
    print(i)