To run MEDUSA4 personal edition, it is supported only on i386 and Ubuntu 12.04 LTS probably has the best support.  Be sure you install the below things.  You need a web browser (to view the help files) but be aware that if you're running firefox outside a chroot and want to launch firefox inside a chroot, firefox doesn't like that, for now.

1. Install chroot of precise.
2. Configure universe and install csh (why csh isn't in main I have no idea, it's Ubuntu?)
3. For the installer to run, install libgl1-mesa-glx libglu1-mesa libxt6 libfreetype6 libxrender1 libfontconfig1 firefox
4. To run medusa, install gconf2 librsvg2-2

Launch medusa from `/opt/medusa4_personal_v5_2_1/master_project/startmedusa`