replace into table name (..some columns..) values (..some values.. ,

IF(creation_time is null, STR_TO_DATE('2017/02/21 18:25:51', '%Y-%m-%d %H:%i:%s'), '')

SET creation_time = CASE
   WHEN creation_time is null THEN STR_TO_DATE('2022-02-20 15:40:58', '%Y-%m-%d %H:%i:%s')
   ELSE NULL
END