Simple Pygame box detection

import pygame

pygame.init()
pygame.display.set_caption('Crash!')
window = pygame.display.set_mode((300, 300))
running = True

#Draw Once
rectplace = pygame.draw.rect(window, (255, 0, 0),(100, 100, 100, 100))
pygame.display.update()
#Main Loop
while running:
    pos = pygame.mouse.get_pos()
    if rectplace.collidepoint(pos):
        print("Don't touch me!")
    for event in pygame.event.get():
        if event.type == pygame.QUIT:
            running = False