5-HTP Supplementation

5-HTP

Dose
Light Theraputic (anxiety): 50mg-100mg Common Theraputic (sleep): 100mg-200mg Recovery Dose (ie comedown of MDMA) 200-300mg (excess of 300mg

Duration
4-6 hours

Onset
30-60 minutes

Effects
Mood Stabilization, Euphoria, sleep aid, antidepressant, appetite suppressant, possible nausea

Avoid
Anything that interacts with serotonin levels or is serotonergic including SSRIs, MAOIs (in large doses), DXM, MDMA (during or before)

Aliases
5HTP
5-Hydroxytryptophan
Tryptophan
L-Tryptophan
oxitriptan

Summary
An amino acid that is the precursor to serotonin. 5-HTP is sold over the counter in the United Kingdom, the United States and Canada as a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid. It is also useful in the recovery from certain psychedelics that drain serotonin such as MDMA (See ~drugs 5-HTP MDMA

Categories
Mood stabilizer, Anti-depressant, recovery

Half Life
The biological half-life of 5-HTP ranged from 2.2 to 7.4 hours, and the plasma clearance ranged from 0.10 to 0.23 1/kg/hour

After-Effects
Minimal, slight depression/anxiety after repeated use

MDMA
MDMA and 5-HTP are dangerous when done at the same time. However, 5-HTP can mean a world of difference for recovering from MDMA and other drugs.

One must use 5-HTP AFTER your MDMA high fades and the dysphoric comdown begins. Wait AT LEAST 5-6 hours after the last dose of MDMA.

The basis for doing this is that 5-HTP is a necessary precursor for the brain to produce more serotonin, and MDMA use depletes a person's natural serotonin levels, thus taking 5-HTP after consuming MDMA is speculated as helping improve serotonin production.

5-HTP should be taken with EGCCG(Green Tea Extract). EGCG paired with 5-HTP promoted accumulation of serotonin in the brain instead of the periphery. This is important because free 5-HTP in the bloodstream and cause cardiovascular complications.

See section 5.2 : http://examine.com/supplements/5-htp/