check.py

import sys
import subprocess as sb
from hashlib import md5

cases = (
"""
ATG      2e4a906c44a96fe84134bf4346adf11c
C        e3648b8960967463784818c3eee57246
TTT      6028a90b05775905ef1a00e7a45463c5
TAGCAT   3b834d2b7b9adc4113ffabd52d354c41
GATTACA  a19463f965c641d071e07da59d64a418
""").strip().split('\n')

for input, checksum in map(str.split, cases):
    proc = sb.Popen(sys.argv[1:], stdin=sb.PIPE,stdout=sb.PIPE)
    output = proc.communicate(input.encode())[0]
    output = b'\n'.join(map(bytes.rstrip, output.rstrip().split(b'\n')))
    checksum_output = md5(output).hexdigest()
    assert checksum_output == checksum, input