callback_hackery()?

''' Consumer '''
import pika

class MegaIntrepidClass:
    awesome_attribute = None

    def callback_check_url(self, ch, method, properties, body):
        # Do something like the below
        # self.hold_it_against_me(body)  # Obviously can't do this "as is".
        print(" [x] Received %r" % body)
        ch.basic_ack(delivery_tag=method.delivery_tag)

    def run(self):
        connection = pika.BlockingConnection(pika.ConnectionParameters('localhost'))
        channel = connection.channel()
        channel.queue_declare(queue='queue', durable=True)
        channel.basic_consume(self.callback_check_url, queue='queue', no_ack=True)
        channel.start_consuming()

if __name__ == "__main__":
    mic = MegaIntrepidClass()
    mic.run()

''' Producer '''
import pika

if __name__ == "__main__":
    connection = pika.BlockingConnection(pika.ConnectionParameters(host='localhost'))
    channel = connection.channel()
    channel.queue_declare(queue='queue', durable=True)
    channel.basic_publish(exchange='', routing_key='queue', body='Hello World!')
    print(" [x] Sent!")
    connection.close()