RegistryKey baseKey;

if (!String.IsNullOrEmpty(remoteName))
{
    baseKey = RegistryKey.OpenRemoteBaseKey(hive, remoteName, regView);
}
else
{
    baseKey = RegistryKey.OpenBaseKey(hive, regView);
}

var key = baseKey.OpenSubKey(keyPath, RegistryKeyPermissionCheck.ReadWriteSubTree, RegistryRights.FullControl);

if (key != null)
{
    RegistrySecurity rs = key.GetAccessControl();

    rs.SetOwner(new NTAccount(domainName, userName));

    if (removeInheretence)
    {
        // Removes Inheretence
        rs.SetAccessRuleProtection(true, false);
    }

    // Gets a list of explicit ACL's And Removes Them
    if (removeExplicitPermissions)
    {
        AuthorizationRuleCollection aclRuleCollection = rs.GetAccessRules(true, false,
        typeof(NTAccount));
        foreach (RegistryAccessRule aclRule in aclRuleCollection)
        {
            rs.RemoveAccessRule(aclRule);
        }
    }

    rs.SetAccessRule(new RegistryAccessRule(new NTAccount(domainName, userName),
    RegistryRights.FullControl, AccessControlType.Allow));
    rs.AddAccessRule(new RegistryAccessRule("System", RegistryRights.FullControl,
    AccessControlType.Allow));

    if (administratorFullControl)
    {
        rs.AddAccessRule(new RegistryAccessRule("Administrators", RegistryRights.FullControl,
        AccessControlType.Allow));
    }

    key.SetAccessControl(rs);
}