df = pd.DataFrame([[2,False,False,False,False,False], [2,False,False,False,False,False]])
print df
   0      1      2      3      4      5
0  2  False  False  False  False  False
1  2  False  False  False  False  False

df = df.ix[:,(df != 0).any(axis=0)]
print df
   0
0  2
1  2