Master Page
     Has few User Controls
     Content Pages
         Inherit from Base Class
     User Controls within Content Pages

Page.master.findControl("label").Text = myClass.Setting1

public class SettingsData
{
  public string Setting1;
  public string Setting2;
}

public static class DataHolder
{
  public static SettingsData Settings = new SettingsData();
  static DataHolder()
  {
    // open connection to db and query for values
    Settings.Setting1 = <value from db>;
    Settings.Setting2 = <value from db>;
  }
}

Label1.Text = DataHolder.Settings.Setting1;