1) Sphere of the Wounded Lion (based on Leo. Housed inside the Gunleon; is powered by and causes physical pain in its user. It is owned by Rand Travis and Mel Beater.)
2) Sphere of the Sorrowful Maiden (based on Virgo. Housed inside the Nautilus Carver, the main weapon of the Virgola Glory [And later, Virgola Glory S], and is powered by sadness and sorrow. It causes its user to slowly lose their five senses. It is owned by Setsuko Ohara.)
3) Sphere of the Swaying Scales (based on Libra. Housed inside the VX System, which powers the DM-Buster Unit Brasta/Li Brasta Type T. This sphere is powered by unshaking resolve in the face of misfortune, and causes violent monomania in its user. It is owned by Crowe Bluste.)
4) Sphere of the Lying Black Sheep (based on Aries. Was housed inside the Arietis. It is powered by lies, and forces the user to only make untrue statements; eventually their speech degrades into pure gibberish. It was owned by Aim Liard.)
5) Sphere of the Bottomless Gourd (based on Aquarius. was housed inside Seiohki The Insa. Powered by "love through self-sacrifice", it saps the user's life energy and causes their body to slowly disintegrate. According to Aim, it is one of the most difficult of the spheres to activate. It was owned by the Holy King of Insaraum, Uther.)
6) Sphere of the Truth-Seeking Goat (based on Capricorn. Currently housed in the Shurouga, it is powered by the desire to seek the truth. Asakim Dowen activated its power to counter Aim Liard's lies and kill him. This sphere was not originally Asakim's; he acquired it from another Sphere holder (heavily implied to be Xine Espio from Z1.))
7) Sphere of the Muted Crab - Reacts to internal "emptiness" (clear mind, no emotions). Sphere Act allows you to prevent other's spirit from increasing (basically induced lethargy). Power will break if they show emotions. Owned by Shikuu.
8) Sphere of the Covetous Golden Ox - Reacts to "intense desire". Sphere Act allows the Reactor to steal strength from others, which is why the Wounded Lion is a good countermeasure (since they'll end up stealing pain). Power will break if the Reactor loses their desire. Owned by Elunaluna Burnstraus.
9) Sphere of the Rising Archer: Reacts to a "rebellious heart". Sphere Act causes the opponent to weaken, the harder they attempt to fight back. Conversely, its power breaks if the opponent gives up without resistance. Owned by Australis.
10) Sphere of the Resentful Scorpion: Reacts to "hatred". Sphere Act is the ability to create a "venom" that amplifies the resentments hidden deep in the heart until the opponent goes berserk. The Sorrowful Maiden's Sphere Act can nullify its power. Owned by Barbiel.
11) Sphere of the Quarreling Twins: Reacts to "cognitive dissonance". A core of sorts, to the Twelve Spheres as it integrates and regulates the constituent emotions and mental states the 12 Spheres represent. Its true Sphere Act propagates the power that overcomes contradictions. When Suzune is killed by Advent at Magallanica, the eight gathered Sphere Reactors and Asakim single-mindedly reject Advent's actions, and the Quarreling Twins activates in accordance with the gathered Reactors' wills and reverses the causality of "Advent kills Suzune", miraculously reverting time and saving her. This is a coincidence caused by the Reactors momentarily being of a single mind, and if Hibiki attempted to do the same on his own, he would cease to exist as a human. Owned by Gadlight (Geminia), and later by Hibiki (Genion).
12) Sphere of the Dreaming Twin Fish: Powered by dreams. The dreams of its owner come true, but he will never know happiness. Owned by Asakim (Shurouga).