def getBit(byteArray, bitNumber):
    "This returns bit with bitNumber position from byteArray"
    byte = byteArray[bitNumber // 8]
    return (byte >> (bitNumber % 8)) & 1

while True:
    multiChannelSample = inputFile.read(2)
    if multiChannelSample == b'':
        break

    for channel in range(0, 16):
        singleChannelSample = '+1' if (getBit(multiChannelSample, channel)) else '-1'
        outputFiles[channel].write(singleChannelSample + '\n')

    sampleCounter += 1