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- Very common (may affect more than 1 in 10 people):
- difficulty sleeping, dizziness, sleepiness, headache, diarrhoea, feeling sick, dry mouth, problems ejaculating, tiredness.
- Common (may affect less than 1 in 10 people):
- depression, feeling strange, anxious, agitated or nervous, decreased sexual interest, nightmares, teeth grinding
- sore throat, loss of appetite or increased appetite
- muscle tension or pain, numbness and tingling, shaking, abnormal taste, lack of attention
- visual disturbance, ringing in ears
- chest pain, palpitations, hot flush, yawning
- abdominal pain, vomiting, constipation, upset stomach, flatulence
- sexual or erectile dysfunction
- rash or acne, increased sweating.
- Uncommon (may affect less than 1 in 100 people):
- hallucination, feeling too happy, lack of caring, abnormal thoughts
- convulsions (fits), memory loss, speech disorder, involuntary muscle contractions, dizziness while standing up, migraine
- fast heartbeat, high blood pressure, flushing, nosebleed
- purple spots on skin, eye swelling, hair loss, cold sweat, dry skin, hives
- night-time urination, unable to urinate, increase in urination, increase in frequency of urination, problem urinating
- inflammation of the oesophagus, difficulty swallowing, increased saliva, tongue disorder, burping, haemorrhoids
- joint pain, swelling or stiffness, muscular weakness or twitching, back pain
- chest cold, runny nose, ear pain
- vaginal bleeding, female sexual dysfunction, breast pain, cystitis
- feeling generally unwell, chills, fever, weakness, thirst, weight decreased or increased.
- Rare (may affect less than 1 in 1000 people):
- abnormal tissue masses (growths), enlarged lymph nodes (swollen glands), low blood sugar or high cholesterol levels, intestinal problems, ear infection
- drug dependence, psychosis (loss of contact with reality), feeling paranoid, suicidal thoughts, aggression, sleep walking, premature ejaculation
- coma, abnormal movements or difficulty moving, increased sensations
- increased pressure inside the eye (glaucoma), tear problems, spots in front of eyes, double vision, light hurting the eyes, blood in the eyes, enlarged pupils
- heart problems including heart attack, slow heart beat and poor circulation
- closing up of throat, breathing problems, difficulty talking, hiccups
- bloody stools, sore or ulcerated mouth or tongue, problems with the teeth
- abnormal hair texture or skin odour, bone disorder
- decreased urination, urinary incontinence, urinary hesitation
- abnormally heavy or prolonged menstruation, dry vaginal area, red painful penis and foreskin, genital discharge or abnormal semen, prolonged erection, production of breast milk
- hernia, injection site scarring, drug tolerance decreased, difficulty walking, increase in liver enzymes, widening of blood vessels
- cases of suicidal ideation and suicidal behaviours have been reported during sertraline therapy or early after treatment discontinuation
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