Could somebody please explain this so called "Infrasigma plateau" that has just recently been discovered?

What are the effects?
How do you dose to achieve infrasigma?
317789>> 317804>> 317936>> 318504>> 318512>>


Jonny - Tue, 26 May 2015 22:17:25 EST ID:8A5iH6IO
>>317782 (OP)
I also demand answers immediately!
Without a good enough understanding of dxm pharmacology it's tough to really brainstorm possibilities but this is the second time im hearing about this on /dis/ and yet a quick Google search presents only pic related



cursive !M6R0eWkIpk - Tue, 26 May 2015 22:54:25 EST ID:Dmczvq8n

Fiend we oughtta parse out our work with Mr. White.
Someone adhere rigorously to the 420c ToS please and let one of us know if it would be possible or should even b e looked into at all, if you wouldn't mind.

the point here having two parts; getting a polished peer reviewed hypothesis drafted up
and two, it's fine that these threads pop up frequently, hashing it repeatedly is like a stream polishing stones into a more refined, and sometimes crackin open some fatty carats worth a diamonds yo.
diamonds.. shiny........ gruuuuu.........


ps- if the anon from 2-3 months ago who started the thread on interesting dosing schedules for dxm has a copy of the sched i gave them, repost plox, troip report if you tried it. i think me and Magoo were goin rogue during or after i posted if there was any replies they might be in the bottom of a k-hole with schroedingers condom. lol jk huhhh

Fiend !!1C9jE+w+ - Tue, 26 May 2015 23:39:50 EST ID:yZ631VIJ.
>>317782 (OP)
Ahhh. Infrasigma. It's like DXM's secret level, only accessible by breaking through the world geometry (pic related). It basically consists of taking Plat Ø doses of DXM, several times a day, for several days on end. The formula cursive gave me was 30-50ml Delsym (180-300mg DXM polistirex) every 4-8 hours, which ostensibly comes down to a 5oz bottle per day. I reached Infrasigma on day 3, but I was using all sorts of potentiators (Hydroxyzine, DPH) as well as sometimes taking 2Cs (60mg DXM HBr + 8mg CPM) with my shot of Delsym, so I probably sped up the process significantly, as well as added to the perceived effect with such an anticholinergic load at some point probably becoming noticeable on its own. TBD.

Either way it was like reality just started coming apart at the seams. Instead of a standard DXM experience, where I dissociated myself from the world; it was like slowly dissociating the world from itself. Everything was vibrating, as if matter was getting out of sync with itself. The molecular structure of solid objects seemed ready to just burst apart.
317967>> 318006>>

>>
Fiend !!1C9jE+w+ - Tue, 26 May 2015 23:47:23 EST ID:yZ631VIJ
>>317797
Fallen emailed me recently with some really interesting information about DXM metabolism in relation to DXO, MEM and 3-HM, which in turn have uninvestigated set of possible-effects. Hope he pops in to finish his thoughts. This is what he wrote, before dashing off to finish some IRL things:

"This is one of my most favorite topics with DXM because of how intricate
the metabolization process is compared to other substances. Many substances
just have one process: drug comes in, liver enzymes grab it, another drug
comes out. DXM turns into two drugs that then switch their SAME pathways to
produce one different substance. As far as I know, that's not really that
common. Add in the fact that DXM's metabolization is inhibited by one of
the same iso-enzymes that it is a substrate (broken down by) on and you've
got more novelty to the whole equation. Attached to this e-mail is a
diagram I have labeled (A,) go ahead and take a look at it. It will be
familiar to you as I've probably posted it a million times. Now i'd like to
directly post one of my many posts here to save some time: First, take a
look at this image. Does that look confusing or what? Dextromethorphan's
metabolic process is complicated at first glance, but easy once you
understand a few basics.

Let's start with how opioid potentiation functions and then build upon
that. Your liver has specialized chains of enzymes that handle a great deal
of conversion of many things, especially different drugs. One system of
these enzymes is the P450 enzyme system and we're going to be using one of
the enzymes, CYP2D6, for opioid potentiation and another later for
dextromethorphan "potentiation." You'll understand why that's in quotes
shortly. Opioid potentiation is pretty simple. So are opioids.
Hydromorphone, oxycodone, morphine, heroin: generally it doesn't matter
what opioid you are using (unless we're talking synthetic and
semi-synthetic,) they all are checked in and processed by enzyme CYP2D6. It
just so happens that a lot of drugs *inhibit*, or slow, CYP2D6 which lowers
the rate at which your liver can break down the opioid and your end result
is higher levels of the drug in blood-plasma levels and potentially a
longer effect. Now the obvious problem with potentiating any opioid is that
you're seriously risking an overdose in an intolerant user so that needs to
be mentioned in the interest of harm reduction. That being said, one such
inhibitor of CYP2D6 is dipenhydramine (DPH.) More are: chlorpheniramine
maleate (CPM,) cimetadine, and the most bastard child inhibitors of CYP2D6
are some SSRIs like fluoxetine and SDRIs like bupropion. You know what
isn't one? Bergamottin, the constituent in white grapefruit juice we hear
so much about. We'll get into that later, though.

So where are we? CYP2D6 inhibitors slow the breakdown of the opioid and we
feel a lot higher with less effort. Concepts, baby.

Let's look at that graphic once more and substitute the notion of opioid
potentiation with DXM's potentiation by adding DXM's extensive
metabolization to this framework: Dextromethorphan is broken down by CYP2D6
*and* CYP3A4 into two different compounds. Through CYP2D6 we get
Dextrorphan (or DXO.) Through CYP3A4 we get 3-Methoxymorphinan (or MEM.)
After this conversion has taken place, the resulting metabolites (DXO and
MEM) then flip their previous metabolic pathways (DXO now is metabolized by
CYP3A4 and MEM is now metabolized by CYP2D6) in order to form the final
metabolite: 3-Hydroxymorphinan (or HYM.) This entire paragraph is simply a
text version of that confusing graphic we just looked at.

Hopefully it's clearer now, right? Now it gets more specific: *when we are
talking about DXM "potentiation," we are really wanting to inhibit both
CYP2D6 and CYP3A4 for optimal effects.* Inhibiting CYP2D6 slows the process
of DXM into DXO and inhibiting CYP3A4 slows the process of DXO into HYM.
Notice how I'm only giving a damn about DXM and DXO. There's a reason for
this: a 'good' experience on DXM is actually the result of a ratio of DXM
and DXO working concurrently in your body. Having just DXM or just DXO
would feel completely different as each are two parts of the whole that we
call the Dextromethorphan experience. While that claim is still debated, I
feel that it is just. Do your own research on the different effects that
DXM and DXO have and come up to your own conclusions on that topic. Back to
our points here, we don't need to worry about the MEM and the HYM at this
stage because not only are they poorly researched, as far as I know they
aren't NMDA antagonists so bollocks to that, amiright? I sure hope so! ._.
What are some good CYP3A4 inhibitors? Remember Bergamottin, the constituent
in white grapefruit juice? It's pretty fucking great for that as many of
you are well aware. Cimetadine is another choice, but it is a weak
inhibitor of both CYP2D6 and CYP3A4. Just google the wiki for CYP2D6/CYP3A4
and check under the "inhibitors" table if you want to get a brief overview.
Just remember that when you're adding multiple drugs that inhibit these
enzymes you need to take in consideration the idea of "cross-potentiation,"
that is, your little 25mg of DPH is suddenly two, three, four fold because
of the cimetadine you added. But wait, then that raises the level of CPM
you took! But shit, DXM is also an inhibitor of CYP2D6 so everything in the
cocktail is going up and up! See how this gets complicated fast?
Potentiators for DXM are best kept at minimal levels and especially when
using an inhibitor that inhibits both enzymes. A little really does go a
long way here.

3. DXM "POTENTIATION"

I put potentiation in quotes (and often do,) because I feel we are not
really potentiating what most of us would want out a DXM trip and
especially not to a newcomer to the experience. Since you're well knowledge
in DXM metabolism you know that the pathway CYP2D6 and CYP3A4 both need to
be inhibited to get optimal potentiation out of DXM. That's really the only
way I feel comfortable describing DXM potentiation as DXM potentiation.
Otherwise we're talking Sigma here and not the general character of a DXM
experience. I feel like DXM potentiation is so misunderstood because of the
lack of legitimate knowledge when it comes to DXM's complicated metabolism.
If everyone had a good understanding of it, nobody would think twice about
what they were doing. In the end, it's always education that is the most
important here and everywhere else." —Fallen
317806>> 317835>> 317907>>

>>
Fiend !!1C9jE+w+ - Tue, 26 May 2015 23:47:56 EST ID:yZ631VIJ
>>317805
More Fallen: 4. SIGMA THEORY

So! We get to this now finally! Alright, let me start by saying what Sigma
is not: Sigma is NOT another plateau. Sigma is NOT some kind of magic state
where the laws of biology do not apply. Sigma is NOT particularly something
you want to be doing to your body and mind very often. Sigma is NOT
enjoyable by about 50% of the people who experience it! (This is referenced
in the DXM FAQ and agreed upon by most enthusiasts I've talked to on DF,
Dextroverse, and other sites in the community.) Sigma is really, really
simple: It's DXM and nearly ONLY DXM. What I mean by this is that when
you're doing repeated doses of Dextromethorphan you are inhibiting CYP2D6
SO HEAVILY that nearly none of the DXO can be created out of the DXM over
such a long repeated dosing schedule and thusly you end up with almost no
body high and a pure psychedelic, hallucinatory, mind warping experience of
pure DXM. Keep in mind that Dextromethorphan is only one tenth the NMDA
receptor antagonist and most of your "dissociative"-like classical effects
similar to Ketamine and PCP come from the contribution of Dextrorphan to
the DXM/DXO cocktail. When you're shutting that completely out you're
getting nearly only the DXM and a tiny amount of DXO. This may explain what
your bar graphs actually represent: your dosages and levels of sigma
activity respond exactly like someone who is metabolizing multiple
staggered doses of DXM should look like and that's what we're doing here in
the first place biologically. It makes sense that the sigma experience
would not start until many hours down the line - the DXM levels need time
and more introductions of concurrent DXM administered to reach the levels
where DXM nearly completely blacks out the DXO in your body. This is what
we know so far! We still have no fucking clue what the OTHER metabolites
from DXM and DXO do after that second pass in metabolization.
Remember the graphic! After the first pass in metabolization, the remaining
3-Methoxymorphinan (MEM) and remaining Dextrorphan (DXO) are both
metabolized into 3-Hydroxymorphinan (HYM.) We have just recently found out
that MEM is psychoactive but it's specific properties are unknown or not
studied well enough to be definitive. We know even less about HYM and
that's where this gets very interesting. Sigma is eliminating or getting
close to eliminating DXO so what we're left with is the combination of DXM
and HYM. THIS IS ABSOLUTELY KEY. With a normal DXM experience we are left
with nominal amounts of DXM, DXO, MEM, and a whole lot of HYM. Since we're
left with DXM and HYM and we know that MEM is psychoactive... surely HYM is
as well, right? We can't objectively say that it is, but let's assume it is
for this discussion. Is the combination of HYM and DXM bringing something
to the Sigma experience that we would not get with just DXM alone? We know
for a FACT that those two substances are in the body at peak levels when
reported sigma experience symptoms are reported to be present. There has to
be a connection. There is no way there is not, I mean it's basic biology
we're talking about here. I wish I could give you more speculation that
this, but we simply don't have enough information at the time.
Dextromethorphan probably cannot explain the sigma experience alone and
this would provide an answer. We'll just have to see as the years go by.
This last thought brings me to my next theory, the Afterglow. I'm sure you
are seeing where I am going with this, too.

5. AFTERGLOW THEORY

We all know how wonderful the DXM experience's afterglow is to our anxiety.
It completely eliminates it, gives us a stimulation comparable to
conventional stimulant drugs, and lasts shorter and shorter the longer we
use DXM over the years. We talk about it a lot, but has anyone ever asked
the question: why do we get it at all? Everything is biological. So is
DXM's Afterglow. We're talking about 3-Hydroxymorphinan here. The strange
metabolite we know absolutely shit about just might be the key to unlocking
this mystery! Think about it: what is left in your body after the majority
of your effects wear off? The metabolite! It's common sense, right? What I
really want to know is what neurotransmitters this thing acts upon. Is it
Serotonin? Dopamine? GABA? Acetocholine? What does the bastard do!?! I feel
that once we understand more about HYM we'll be closer and closer to
understanding the DXM afterglow. I'm particularly excited about this
because of the Ketamine research trials with Depression. Imagine how cheap
it would be to come up with an anti-depression drug just from
Dextromethorphan. We could provide help TOMORROW. Ketamine will always be
an option, but DXM is dirt-fucking cheap and more widely available. Plug in
the recent research that has found DXM actually regulates insulin levels
and we've got even more promise to have DXM researched legitimately and
SOON. People need to stop thinking about DXM with such poor regard and
start realizing the power of this little chemical before a great
opportunity is wasted!" —Fallen


>>317798
> anti-sigma
Not at all. It's like pure essence of sigma.
> Effects would be very gradual to the point of not necessarily noticing, but you'll know something is fucky
Very gradual at first, at some point though (for me it was when my friends were like "what's wrong with your eyes?") it became very clear just how fucky things were
317810>> 317813>> 317907>> 318365>> 318609>>

>>
Jonny - Wed, 27 May 2015 03:53:28 EST ID:6+gyyB8i
I can't put into words just how excited I am about all this. Maybe I'll do so later when im not so sleep deprived
God bless u Fiend and Fallen <3

>>
Shitting Fanhall - Wed, 27 May 2015 04:03:15 EST ID:XOF/srR1
>>317810
I can confirm that to be true; when I used to do DXM every day I usually took 300-400 every few hours, for a month

I learned to operate "that world"...it was glorious.
317815>>

>>
cursive !M6R0eWkIpk - Wed, 27 May 2015 06:11:42 EST ID:Dmczvq8n
1432721502616.jpg -(56342 B, 720x405) Thumbnail displayed, click image for full size.
>>317798
>As far as I know
Yea but we all know you dont know shit but you have great taste in graffitti
you cant anti sigma but that's a cool idea. Well you could actually! but not like that obv.
woahhhh
woah Fiend. THE SUBJECT IS GROWING TOO POWERFUL, APPLY THE ANTI-SIGMA SERUM (COSigma), (COΣ) i instantly >>317806'd the idea too, cause, exactly, it would jsut double your power. But  you may be able to just nuke someone's robotrip into a smouldering MEM3-HM hangover before they curse up the joint.
That would require that there was a way to effectively and promptly get more metabolizing enzyme into someone. A shot or tranq gun LoL and that the ROA would get it where it needed to go. If this metabolism is taking place in the liver, nothings saying it's reomtely ok for over 9000 metabolisms happening IN your circulatory system, potentially leaving like all sorts of Bromide, exhaust gases, or enough exothermic heat to boil the blood out of a Sigma Mutants still pumping veins.
Become Based Death Knight

heheh
yea guys let me clear this up again, this happens all the time idkwtf, i think basically it's that we're all guilty of Reading & Robotripping
>stop guessing how much a 5th plateau does for you would be thinking it's Sigma. It's not, you black out.
>dont ask how to hit sigma like it's one singular thing, it's not.
>sigma is coming to be thrown around but basically think of it as tripping on a whole plateau dose ofboth DXM and DXO at any given moment
> any time you dex this is gonna happen Bing- drink drank bang- 1st plat dxm boom-dxm plat over by the time 1st plat dxo peaks. you got nothin
>imagine you had dxo somehow in a bottle like dxm, both 1st plat doses for you. take em both at once. bing-drink dranks bang-SIGMA-ONE Boom-uh oh, might not have seen that com ing but youve got dxo going! how? the orignal dxm ya big dummy. the dxo only bottle is out but the dxm made its own dxo levels
>until you can buy dxo, you cant start off flawless like that. so you have ramp up time where you're just going to be on DXM for a bit
>ADDITIONALLY youve all feltt the sigma effect, you jsut call it the peak. at hour 4 of a normal 1st plat robotrip, you have the most dxm and dxo goign at the same time. one is tapering off one is coming up, so you're 1st plat peak is a little infrasigma giggle for an horu or two
>THOSE OF YOU WHO STAGGER 2 Bottles half and half and say idk i cant find sigma or itys nothing special, a 1st plat and a 1st plat spaced equally will have your first bottles 1stPlat.DXO at its peak when bottle two's 1stPlatDXM curve reaches its own that's how most of you will get to feel a quantifiably accurate SIGMA1.
>do whatever the fuck you want, tus junkies like many anons and myself did it for years just wingin it, cause yourte on drugs not stabilizing a patient at a hospital I cracked the math of what was going on here literally to try and get people to leave me alone from threads exactly liek this lolasdjjladsj;c
um so my shit uses the dosage chart NO my shit MAKES YOUR LAZY ASS go weigh yourself, look at the chart from the 1930s to get your plateau ranges

the reason you're not getting some of the like borderloine actual superhero shit going on that you hear about sommetimes is.. like if you wanna do SIGMA3 and do it right now... basically it's not happening cause even if you funnel whatever that is like 3 bottles of tus then do it again, funnel 3 more timed to hit your first fucky funnel's worth's DXO peak.. i think you'd need all of our livers tripping as a unit to handle that much in that little time, so what's gonna happen from above that i said would?

MAMA SAID KNOCK YOU OUT NIGGA.
dont tesla me you mother fuckers i love you goodnight.

>
317820>>

>>
cursive !M6R0eWkIpk - Wed, 27 May 2015 06:26:50 EST ID:Dmczvq8n
>>317811
Slayer Im so happy to hear that. I love you.

>>
Jonny - Wed, 27 May 2015 08:24:47 EST ID:6+gyyB8i No.317820 Ignore Report Quick Reply
>>317813
WE LOVE YOU CURSIVE!<3
What? Who said that?
That straw hat wearing quellazaire smoking cunt in the poncho, probably

>>
Fiend !!1C9jE+w+ - Wed, 27 May 2015 11:50:23 EST ID:yZ631VIJ No.317835 Ignore Report Quick Reply
1432741823535.jpg -(205233 B, 1800x1209) Thumbnail displayed, click image for full size.
>>317805
This is the graphic that explains shit real well.
317844>> 318331>>

>>
Fiend !!1C9jE+w+ - Wed, 27 May 2015 12:33:46 EST ID:yZ631VIJ No.317844 Ignore Report Quick Reply
>>317835
Okay, so without starting a new thread, let's talk potentiation. I'm looking at lists of CYP2D6 and CYP3A4 inhibitors, and I see Valerian is a dece 3A4 inhibitor, as well as bergamottin (GFJ). Cimetidine is mentioned a lot but I think that's Rx in the US. I'll take a look next time I go to the pharmacy For CYP2D6 the obvious choice is DPH, but all antihistamines are good. I'm scripted Hydroxyzine which is dope for potentiation. CPM is really good. I'm also looking at Clemastine, which I had never heard of, but as Wiki says "Unlike loratadine or fexofenadine, clemastine is a sedating antihistamine, however it exhibits fewer other side effects than most of the widely used antihistamines.[citation needed] Clemastine is also classified as an antipruritic (i.e. it stops itching)." So that sounds interesting.

I'm gonna build a stack of potentiators, with all of those things, and see how far I can get. I wonder if I can speed up access to ∑ by using a bunch of inhibitors, with fewer DXM doses. Gonna stack:
> Valerian
> Hydroxyzine
> Bergamottin
> CPM
> DPH
> Poss Clemastine and poss Cimetidine if I can get them
With all that, I bet, well it's possible, that I can reach ∑ with 2 doses. First one should be a 6-7mg/kg polistirex dose, second one should come at t+5:00-t+6:00 slow-dosed 7-8mg/kg HBr dose.

I'm gonna try this ASAP, but I'm not sure if I can get around to it today. If anyone has most of the things in that list, and a bunch of free time, do it for science; otherwise I'll get on it sooner or later.
317856>> 317869>>

>>
Fiend !!1C9jE+w+ - Wed, 27 May 2015 13:10:07 EST ID:yZ631VIJ No.317856 Ignore Report Quick Reply
>>317844
Also mentioned under 2D6 inhibitors is CBD, which explains the distinctly synergistic properties of weed and DXM.

Jonny - Wed, 27 May 2015 14:10:47 EST ID:snAupebC No.317871 Ignore Report Quick Reply
>>317856
I think someone posted this link here in dis a week or so ago but here it is again
http://m.dmd.aspetjournals.org/content/39/11/2049.full
I always had an inkling that something was up with weed potentiation. The intensity's uncanny

>>
Fiend !!1C9jE+w+ - Wed, 27 May 2015 15:04:26 EST ID:yZ631VIJ No.317883 Ignore Report Quick Reply
>>317869
Cimetidine is available on Amazon. I primed a bottle, along with Valerian, that'll be here on Friday. I'm gonna take a trip to all the pharmacies in my heighborhood (in NYC, there are at least 10 pharmacies within 1/2 a mile) and see if I can't track down some Clemastine. Both Sandoz and Walgreens make OTC tablets, but almost nobody sells them.

As for suggestion for you:
> Start with 100mg DPH and 50ml Delsym
> Add 50-100mg DPH and 30-50ml Delsym every 4-8 hours.
> Take DPH at night to get you to sleep
> Dose Delsym last thing at night before you go to sleep and first thing in the morning
> Add 4-8 cough gels to your shot of Delsym whenever you feel like it. I suggest saving that for day 2-3 though, because by then the HBr will be ∑ worthy, and you can get a good kick out of a fuller dose if you so decide.
You're gonna need more though. You've got 2 1/2 days there probably. Should get 1 more bottle of gels or another 3oz or something. IDK. You can play it by ear and always get more when you need it.

This is all assuming you're trying to get to infrasigma, if you're trying to stack potentiators and shit I'm not sure what's best. I can say that going for a single day ∑, polistirex is not ideal, even with potentiation. The going up and then down is part of the ∑ experience. Infrasigma is different in that it creeps up, whereas full ∑ is like just falling into some unexpected quicksand of drugs.
317891>> 317914>>

>>
Fiend !!1C9jE+w+ - Wed, 27 May 2015 15:44:07 EST ID:yZ631VIJ No.317891 Ignore Report Quick Reply
>>317883
Also it turns out that the white grapefruits are totally not necessary. All grapefruits have similar bergamottin content (which surprisingly obviously is most present in bergamot oranges) so any GFJ will do. I myself may look into bergamot extracts and or actual bergamot oranges poss—

I'm getting far more into this than I anticipated.

>>
!AzariXzZFc - Wed, 27 May 2015 17:22:15 EST ID:puoCN8z+ No.317901 Ignore Report Quick Reply
I don't think there is any plateau called 'infrasigma'. The whole concept of 'sigma' is already just pure grey area and speculation.

Infrasigma sounds like a word that cursive made up after her 4th day spun out and on syrup. Yes, i'm sure if you do cough syrup for two days straight and take 5 doses spread out that you will feel much different than normal. I don't think we should give that feeling a label though and try to have goals to attain it, lmao.

Don't get me wrong, i've dosed for three days straight before too. It was interesting and definitely felt different starting around day 2 and a half, but I wouldn't call it a special state on it's own, i'm pretty sure I was getting closer and closer to the limit of reality with my body. I have only a few faint fuzzy memories of those times, and although they felt pretty unique, it just kind of felt like I had realized I was dreaming while I was still in a dream. If you've ever had that happen, it's just like that but you aren't sleeping and you can't wake yourself up. I would never recommend anybody to repeat this though, as at the time I was just depressed to the point of exploring the headspace of chemicals to see how far they could be pushed, using my body as a tribute if anything went wrong. I pushed real far, sure, but I was not able to really use the DXM headspace (at those levels, dont get me wrong a regular dxm trip is therapeutic as fuck for just about anybody) for anything that helped me short or long term. I dosed at least 240-480mg a day for just a little over three months while still participating in society, working at a grocery store had my own apartment with my girlfriend etc etc. The dxm really fucked things up, I thought it was leading me to answers but it was just giving me a comfy space to go to when I needed to run. Abuse of these comfy spaces can really let you forget about what is happening around you. It took me about a year and a half until my brain felt normal again.. until all of the racing thoughts in the back of my mind were able to quiet down to a point where the world wasn't a questioning of reality every time I opened my eyes. DXM made me very paranoid about the world with the 'revelations' i thought on it. It kind of trapped me inside some explanations for reality that were very hard to convince myself otherwise. Abuse of this chemical is not something I would recommend, as there are far many other chemicals out there right now that provide the same enjoyment with little to no physical and mental side effects in comparison. MXE has been my absolute favorite for the last few years, and 3-meo-pcp gives me those first-time-dexing feels whenever I need it.

Sorry this post started as something different and went into a spam about abuse. Been seeing a few recommendations on this board that I really wanted to give my 2cents on lately. You don't have to follow my advice, I just want people to know about my experience. I was stubborn and wouldn't believe anybody until I found out for myself too. I just could have saved my physical and mental states a lot of time if I had been smarter in my exploration. I really do feel long term cognitive effects from all that syrup.. stumbling over words, forgetting sentences halfway through them, stupid shit like that.

Like I said before, the main point I want to get across is I totally understand wanting to explore our heads to the fullest- just know that you only have a limited amount of processing power and time with your physical body. If you buy a car and then drive it across the country 5 times over the first year you have it, you should expect some issues to arise that cars who haven't been driving around a lot won't experience. If you want your car to last the longest, you can still take those extensive lengthy trips, but you need to really maintain the shit out of it. And you can't go too hard at once.

Love and light, hope everybody has more fun this time around than last, and that next time around is even better.
317906>> 318450>>

>>
Fiend !!1C9jE+w+ - Wed, 27 May 2015 17:43:54 EST ID:yZ631VIJ No.317906 Ignore Report Quick Reply
>>317901
> I don't think there is any plateau called 'infrasigma'. The whole concept of 'sigma' is already just pure grey area and speculation.
It's not a plateau in the traditional sense, neither is full ∑. The whole point of ∑ is that it destroys the concept of plateaus, in favor of something far more difficult to quantify. It is mostly speculation, but there are certain things we know (see everything Fallen wrote), and certain things we experience (see every ∑ report ever), that point to a grey area, that really deserves the speculation required to make it less grey.

> Infrasigma sounds like a word that cursive made up after her 4th day spun out and on syrup
Well she did invent the word. I don't know what state she was in though. Lol.

nb
318365>>

>>

These types of posts are the reason I love /dis/. So much YES. I didn't even know infra-sigma exists. But that totally jives with my understanding of how dxm metabolizes. And of course /dis/ has been sucking for the last month or so, and then I read a glorious post about dex while I'm dexxed for the first time in months. Synchronicities, eh? DXM is weird like that, things seem to happen or fall into place exactly how I plan them to when I'm dissed.

Ebenezer Billerfoot - Thu, 28 May 2015 00:17:08 EST ID:9fuT1dIV
So if i'm reading things right, it seems like there are only about 4 things that are for the most part safe and easily available that inhibit CYP2D6; the anti-histamines DPH, CPM and Clemestine, and CBD. I'm unfamiliar with Clemestine (if anyone has used this to potentiate or has knowledge contrary to my claim step forward for the good of /dis/) but I've definitely used DPH and CPM (as i'm sure many of you have) I'm not really into all that heart racing, especially since DXM does enough of that on it's own. CBD is a variable i'm interested in experimenting with, especially since i have access to straight CBD oil. Anyone ever go that route instead of just smoking weed?

In the CYP3A4 camp, there's a number of readily available potentiators including but not limited to; Valerian, Begamottin, Star fruit, Pomegranate juice, milk thistle and Gingko biloba.

Now, if anyone has any anecdotal evidence about how strong each of these potentiators are, i'd love to hear it.

My personal plan is to get some CBD oil from my boss (He has at least an oral syringe if not a tincture of it, he's all about cannabis in all forms) and take some gingko biloba capsules (1-2 every hour) probably for the day before and the day of my trip and see what happens. I'm not too interested in infrasigma since I live with my grandparents and couldn't really spend all that time fucked up, but the information about low inhibition of both P450 was priceless.

Sorry if this was uninformative or naive, I don't have that strong of a grasp of these things and used Wikipedia as my source, so if i've got any mistakes please let me know or if you've used any combination of the aforementioned substances with DXM, let me hear your results!
317939>>

>>
Kerflap !HUZ.4c6SGE - Thu, 28 May 2015 00:29:05 EST ID:3vHvRt9a
>>317782 (OP)

I'll have to try this out. I've got some time to waste right about now so I can prolly do this. Will have to plan accordingly so I'm not fucked up at a bad time though, but if I ever wanna be able to do this I'll have to do it soon. I'll have to hit up like 3 different stores to get enough for it, but I feel it should be worth the trouble. I'll get triple C to speed up the process.
318475>>

>>
!AzariXzZFc - Thu, 28 May 2015 00:44:08 EST ID:puoCN8z+
Hey, I got really high tonight and read through your post again. That is some really good stuff. I'm glad people are taking the time to learn it as thoroughly as you. You set a good example. The talk in this thread of 'plateau sigma' is much much much much better than threads a few years ago.. there used to be so much magical speculation lol. It seems like you guys are narrowing it down though.

>Alright, let me start by saying what Sigma
is not: Sigma is NOT another plateau. Sigma is NOT some kind of magic state
where the laws of biology do not apply. Sigma is NOT particularly something
you want to be doing to your body and mind very often. Sigma is NOT
enjoyable by about 50% of the people who experience it! (This is referenced
in the DXM FAQ and agreed upon by most enthusiasts I've talked to on DF,
Dextroverse, and other sites in the community.)

Seeing this posted in a thread about sigma is almost like an achievement lol.

sorry if this is kind of straight laced / no fun or whatever, reading back through it i seem real bland but meh. lately ive been on a kick to really get down to the nitty gritty with things.. i really wish i had access to lab equipment. it's been fun learning how to read chemical analysis testing though, I ask all my vendors for results if they have them handy. most of the time you can request NMR / GCMS / LCMS and they will have it on hand. MXE has been my focus point lately. I want to find out why this one vendor I have is so goddamn amazing compared to the rest. I need to be able to test for isomers somehow I think. I really think the s-isomer mxe is different. for many chemicals it doesnt matter but idk. anyway.

I agree that there is definitely some science to be learned behind the difference between DXM and DXO levels, but I am a person that needs to see it to believe it. I am not sure how to chemically test a substance that I have to see what it contains, or a solution that I make to see what it contains. There is no way for me to do any accurate science or thinking regarding DXM/DXO levels without proper equipment. To go even further, there is NO WAY that I can accurately start making any hypothesis regarding mental states associated to doses of these chemicals before I am able to even understand exactly what I am working with. I do not feel safe, smart, or accurate reading Wikipedia to 'learn about dxo and how it metabolizes' as my pre-requisite learning before going off and creating dosing regimens, recommendations, or anything of the sort related to a high from these chemicals. 'Dextromethorphan Hydrobromide', the ingredient that I am able to find in over the counter cough syrups and powders online, is told to have interesting ways to metabolize in the body. I am not exactly sure how people who discuss the metabolization process know what they are dealing with, but I assume they have the proper chemical analysis equipment in order to tell what is going on.

When DXM HBr is ingested into our bodies, our chemical forge also facilitates this conversion, but NOT VERY WELL AT ALL. This conversion happens via the CYP2D6 Enzyme, which many of you are familiar with. Inhibiting this enzyme from doing it's natural process (through the use of things like White Grapefruit Juice or other things frequently discussed on this board) will cause your body to produce LESS DXO and ingest MORE DXM. There are many speculations on different feelings from different ratios of these two chemicals. I cannot say either way, even after extensive research and application.

To you guys who are looking to explore further with this though, I found a good post online explaining how to convert it before ingesting:

" You cannot cleave the methyl group with citric acid. You have to use excess HBr or HI on a phenyl ether to produce an alkyl halide and a phenol. In terms of reactivity toward the cleavage of ethers, the hydrohalic acids are as follows:

HI > HBr >> HCl

I didn't think that HBr could do it but apparently the bromide ion is a good enough nucleophile. Citric acid and the like are much weaker nucleophiles than hydrochloric acid so there's no way in hell they could cleave the methyl group.

The reaction occurs as such (I'll use hydroiodic acid as the example):

[DXO]- Means the rest of the DXO molecule, with whatever is attatched to the 3 spot (the phenolic bond) represented externally.
(so "[DXO]-OCH3" would actually be DXM and "[DXO]-OH" is actually DXO)

The reaction takes place in excess HI.

1) The oxygen attatched to the phenyl group becomes protonated.

[DXO]-O-CH3
|
H

2) Transition state: The bromide ion starts forming a bond with the methyl carbon atom and the bond between the methyl carbon and the oxygen begin to break.

Br-
|

|
[DXO]-O- - -CH3
|
H


3) The reaction is completed, leaving DXO and iodomethane.

CH3I +

[DXO]-OH = DXO


There are two practical applications of converting DXM to DXO:

1) It seems that many people find a high ratio of DXM to DXO unpleasant, so in this way the ratio could be controlled.

2) CYP2D6 individuals cannot tolerate DXM because they cannot efficiently convert DXM to DXO and are left with a high ratio of DXM to DXO. This would give those individuals a chance to enjoy the drug.

The other application would be for the DXM enthusiast to explore different ratios of each substance and report on the differences between each chemical. "
317981>>

>>
!AzariXzZFc - Thu, 28 May 2015 00:49:43 EST ID:puoCN8z+

I just found this online regarding CYP2D6 inhibition.
> Most of the extracts had a weak or negative inhibitory effect
towards CYP2D6 activity. The most inhibitory
product was NRP 295 which inhibited 25.2% of
CYP2D6 activity.
No clue what they are talking about but maybe you can find out more -http://www.researchgate.net/profile/Heather_Boon/publication/51059328_Inhibition_of_human_cytochrome_p450_metabolism_by_blended_herbal_products_and_vitamins/links/0fcfd5085705f19c9c000000.pdf


also i just wanted to give a shout out to cursive specifically. i know i may talk a lot of shit but i have mad respect for you. you are one of those people that just go to show we are able to create whatever character we want int his mmo we all log into every day.. no limits. that deserves an honorable mention, regardless if anyone agrees or disagrees with what you choose to do.
nb

>>
Kerflap !HUZ.4c6SGE - Thu, 28 May 2015 04:23:04 EST ID:3vHvRt9a
If I made every other dose hbr, could you still reach infrasigma? It seems like it would be cheaper seeing as I don't steal the shit. Also less running around to get the stuff.
317973>> 317980>>

>>
Edwin Gorringwere - Thu, 28 May 2015 10:18:52 EST ID:AsxcGgS5 No.317973 Ignore Report Quick Reply
>>317967
just use the internet dingus

>>
Fiend !!1C9jE+w+ - Thu, 28 May 2015 12:09:15 EST ID:yZ631VIJ
If you use HBr, you'll need to dose more often, which in turn probably means buy a lot more stuff honestly. The 888mg poly in a 5oz is by far the most DXM you can get in a single bottle of product.

If you want to save some money, I would split every dose 1/2 poly 1/2 HBr, instead of alternating between them. And still save that for later. Day 1 I think you're probably best off using all poly and potentiators, just to build up as much of it in your system as possible, before getting to the HBr doses which are gonna be more— punchy.
318014>> 318289>>

>>
Fiend !!1C9jE+w+ - Thu, 28 May 2015 12:10:07 EST ID:yZ631VIJ
Fuck. I have no idea about the chemical reactions involved in getting pure DXO. Shit. I just know what it feels like to slam a fat dose of HBr, vs. slow-dose vs. re-dose, vs. dose poly. And everything I say about DXM/DXO ratio is, as I admitted before, just speculation based on the continuity of my personal experience. Lab testing has nothing to do with this, unless there's a way to continually monitor the blood levels of DXM, DXO, MEM, & HYM all at once. So the best we can do is talk about our various dossing regimens and how they seemed to work, and try to create a working hypothesis just by gathering as much data as possible, even if that data can't really be quantified, just recorded for what it is.
People didn't know jack shit science when they invented the plateau system. And it's not perfect at all, really only applying to a single, slammed, unpotentiated dose; but it's still a useful model, if only as a point of reference. So it is with our ∑ "formulas."
>>
NCACEDEADDEL - Thu, 28 May 2015 16:11:44 EST ID:Q2Pud5XC Could you give a more "accurate" description/report of this infrasigma please and thank you? I am striving to know how it feels before I attempt anything..I have been taking DPH regularly,, have done DXM poly before, triple c's, dramamine, ect, robogels, yup. Please reply back

NCACEDEADDEL - Thu, 28 May 2015 16:16:08 EST ID:Q2Pud5XC No.318007

Fiend, feel free to use as much descriptive vocabulary diversity as you please, I would really like to hear about how this felt and if it hit you like a train unexpectedly after thinking it was never going to come VIA you said it creeps

>>
Fiend !!1C9jE+w+ - Thu, 28 May 2015 16:25:39 EST ID:yZ631VIJ
Okay, I was about to say "I'm not sure what else to say," but you gave me a good writing assignment. Or at least, I took it that way since I call myself a writer. I'll spend some time on it tonight. I took some Delsym so I should be in prime position to recall creatively. I'm sure if I think about it I actually have a lot more to say.


>>
Kerflap !HUZ.4c6SGE - Thu, 28 May 2015 17:03:06 EST ID:3vHvRt9a


I went out today and got two 5oz delsyms, one 3oz delsym, and a box of 16 triple C. In just a minute I plan to try out infrasigma. If what I have isn't enough then I'll wait till a (more) sober point and go out to get some more bottles.

My plan for dosing is to start big, I'm gonna take half this 3oz now with 4 triple C, after 4hrs or so I'll take the other half with 2 more triple C, then after this I plan to take it every 6 hours with 2 triple C every dose, at night I plan to take 50-100mg DPH so I can sleep easily and potentiate the dxm further. I'll write a mini trip report soon as it starts kicking in and then after every dose. wish me luck fiend, cursive, and friends.
318014>> 318029>>

>>
Kerflap !HUZ.4c6SGE - Thu, 28 May 2015 17:13:46 EST ID:3vHvRt9a No.318014
Oh, forgot to mention. I have cigs, 24mg ejuice, and weed to also potentiate, and I'm going to try my best to score some lsd or shrooms or some other psy that I can take at the end with my last dose to REALLY make things crazy. HERE WE GO. 44.5ml of delsym going down!

Also, fiend, in response to >>317980, I can buy a gram of DXM hbr for 6.50 which would make for 5 doses of hbr, which is much cheaper than 888mg poli (effectively 444-666mg) for 13-20 dollars. I do understand you have to dose more though, but I think if this first amount doesn't do it I'll grab a bottle of that with my delsym to help out with dosing.

double post; nb.
318035>>

>>
Fiend !!1C9jE+w+ - Thu, 28 May 2015 19:14:52 EST ID:yoIIfBOu
Sounds like a solid regime. Report back in 48 hours.

SummerOfSigma !7zAMOtdUD2 - Fri, 29 May 2015 00:48:38 EST ID:CbA6ouk2 What dose the dxm/dxo ratio look like over time for delsym from dosing by itself? Im curious about sigma because I hit it accidently. Im not sure if 7 trips in 2 weeks, mixed with my poli/hbr slam, or if the ratio from delsym and the added hbr in the middle of the trip was the key. It was a very enjoyable level of sigma without delusions. Just clarity, insanely fucked up, and I felt like I was truly seeing into what dxm really was. Every trip after has felt like looking at the photograph instead of being there. The visual distortions on the world around me were incredible. My favorite effects we're probably people in movies looking like caricatures almost, and being able to read 3 lines of text per second(while your eyes may be able to read it all your brain doesn't keep up for long)
Ive recently just gotten into the psychonaut business myself. I always fucked around with drugs but never seriously. Ive only got one sigma and a boatload of 2nd plateau trips for dxm, got mad deeeep into the underbelly of the shrooms(even talked to them a little), and am trying to dabble with lsd(though all I keep finding are weird tweaky research chems fml). Hopefully one day Ill be able to safely enter sigma while on lsd+shrooms(#squadgoals) Until then, I'm just gonna keep fucking around with my dxm doses. Finally moved out into a place I can trip whenever I want, and I dont even need to work that much to pay rent. I can trip on psychedelics 3 times a week for a while and still be able to keep up with work. Dxm I havent binged on seriously besides every other day for 2 weeks of mid/up 2nd plateaus, even then I wasn't dissociated from reality at all. Dont know about constant sigma though
I offer myself up to this board as a lab rat to dxm! FOR THE QUEEN
318052>> 318057>>

>>
Fiend !!1C9jE+w+ - Fri, 29 May 2015 01:12:47 EST ID:yZ631VIJ No.318052 Ignore Report Quick Reply
>>318050
Other way round. Enter /psy/ from ∑.
318055>>

>>
Fiend !!1C9jE+w+ - Fri, 29 May 2015 01:57:16 EST ID:yZ631VIJ No.318055 Ignore Report Quick Reply
>>318052
Longer <∑ TR, as promised:

It started out innocently enough. Day 1 was lighthearted, and a little bit silly, but nothing more. By the end of the day I was lightly intoxicated if anything; tipsy perhaps. My nightly 150mg DPH was a little extra trippy in the CEV department. And I fucked like a beast; a little hypomanic perhaps.

The second day was dreamy in the morning. I walked in a cloud, a very pleasant one at that. I was smiling most of the time. But as evening turned to night things started getting funky. Lights were intense– Not bright exactly. It was more like an Instagram filter with the contrast turned way up. Light and shadow, and the lines between them were crisp, and yet almost fluid between each other. The entire ground seemed to have a skin on it, somewhere between carpet and wallpaper, that was made of light and shadow; and it would dislocate itself from the actual ground sometimes, like floating a few mm above the surface, especially in places where there were multiple light sources casting multiple shadows on a single object. My sense of hearing and of smell both seemed to be hyperactive. The fog had cleared and was replaced by a kind of— cock-eyed– ness. Everything was just so slightly off kilter; like instead of the standard DXM liliputian hallucinations, it was more like perspective had been fucked a little, so that lines didn’t exactly converge the way they were supposed to– I suppose. I had sex in the middle of the day, but by night-time, even with the aphrodisiac effects of my DPH, my dick was broken, not to return until 20odd hours after my final dose.

The 3rd day was when things got really interesting. I woke up in the morning, took my shot of Delsym and my Hydroxyzine and what have you, and it felt like less than an hour and I was in the rolling waves, foothills of <∑. When I say rolling waves, I mean it several ways, long rolling waves like out at sea, pushing across the surface for miles, somehow I was riding them; among them; cursive has several times referred to a “sigma roll” and it makes perfect sense. It was a bit like rolling on MDMA in the just flowing sense, of time being an unstoppable force, wheras dissociation usually destroys time, and time was certainly destroyed, it was progressing rapidly whether I was up to speed or not, and like rolling I kinda just went “Well shit; alright,” and kept rolling. But the waves— it was a sea that was rolling, not me; a sea rolling beneath me, around me.

Things were all fine and dandy until my 3rd or 4th dose of the day. I think I took 8Cs (240mg HBr + 32mg CPM), but that doesn’t make sense in retrospect, because at that point I was already pretty deep, and I don’t think I would have fucked the experiment, unless I had already decided to call the experiment off after 3 days and took one last dose— More likely I took 4Cs and 40ml of Delsym or something, but regardless, it kinda broke a line, not for me exactly, but for other people. “What the fuck is up with your eyes?” — Fuck. The jig is up. “Are those– DXM eyes?” — Fuck. Double jig upped. As far as I was concerned the continuum hadn’t really changed; I was getting progrssively, but linearly, deeper into the etherial mire; but apparently my demeanor turned relatively quickly. When they asked when I did it, “Well…” I’m not sure what I said, but it was enough explanation for them to say something like “Yeah, wow. I dismissed any goofiness before, but your eyes.”

In my head I was still on the same timeline, but somehow my mouth had stopped working properly. Maybe I did take 8Cs and the CPM /del/ cat got my tongue. I’m not sure. All I know is that my working memory was shot, and my ability to carry on a conversation was limited. I would sit around and listen, perfectly capable of following what was going on, but only rarely successfully forming and voicing a coherent sentence. That was part of what tipped them off too. Usually I’m pretty chatty unless I’m in a bad headspeace, and they, being my good friends, noted the silent smiling and nodding as very uncharacteristic.

That was also the point where (even in the linear progression it seems that there were significant moments, points on the timeline) I kind of admitted to myself how thoroughly destroyed reality had been. Matter was coming apart, as if the molecular structure of everything had become violently unstable. Everything was simmering almost, ready to boil, or explode, or disintegrate at any moment. The edges of obgects kind of blipped for one place to another; such that the object appeared to kind of be in several places at once, leading to the afformentioned molecular structure analogy. Everything was vibrating on some metaphysical level. I was walking through— I don’t know— a fucking 4 dimensional electromagnetic field— or some shit. It was just breaking down.

I had only one more day with my friends, and I had gotten far deeper far quicker than I expected. I proved what I needed to prove, and called it after the 3rd day. I was glowing for a solid 36 hours, then off kilter for like 3 more days. It was probably 5 days before I was totally baseline though. Shit was whacked.
318164>> 318290>>

>>
cursive !M6R0eWkIpk - Fri, 29 May 2015 02:21:42 EST ID:Dmczvq8n
the come up is longer due to the polistirexbeads surrounding the DxM acting as a time release as the body's terrifying juices sadistically slow disolve it. peak at 6hrs, gone after 12 sounds and feels right. 12 hour relief it says on the boxes. There are a few ways that could be used to alter the equation of the DxM curve, you'd have to ask delsym i guess.

The conversion to DxO has nothing to do with the beads. The Beads melt, DxM is free to enter the bloodstream and do what it always does, including being metabolized at a rate converse(?) to the rate for the DxM for the come up only(?), after which it, falls off at a rate congruent to DxM's fal-off*
*This assumes equivalent time(t) to metabolize DxM and DxO. In my old notes and scribble-pads there's a footnote to find the exact curves from an external source. Qualitatively i'd say it feels accurate.. maybe. i wouldnt be surprised if the DxO afterglow lasted x2 or x3 what the DxM comeup is. It feels like it sometimes. I sometimes take Potentiators that limit ammount my sweet liver juices to metabolize it, i could be feeling that, i could also be feeling the other 2 metabolites exgtending the afterglow a little bit.

pic related to HBr's curve. the Poli one would have the pink curve of dxm stretched over 12 6 up 6 down. its DxO would come up over 6 hours but fall off over 4. wait.
yea need a second opinion. Could be 8 come up, 4 come down for both. every particle of DxMpoli that makes it out of the digestive tract and into the blood, it is beyong the aid of the not digested poli plastic cancer, poli, HBr and freebase sholuld all identical.

Okay, again with the whole DISCLAIMER: I DON'T KNOW SHIT.
From personal experience and a very minimal understanding of edible plastics. Some of the DXM drops immediately, then rises to a peak at about the 3-4hr mark. That's the peak, but from there it seems like there's sort of a constant drip of Dex, not making one higher, but maintaining a constant level until about t+8; at which point the polistirex has been mostly digested, and shit starts coming down. 12hrs is very accurate. I'm convinced Delsym was created deliberately with intention ofincreasing abuse potential.
>>318058
Here's the graph that took me 3 years to understand. But I get it now! I'm not sure I can explain it better. Just stare at the image for a while. See if anything comes to you. I don't know. None of it made any sense until I actually went to â ˆ ‘. Then it all fell together.

Also, I got mail. I have Valerian, Cimetidine, Hydroxyzine, DPH, and I'm gonna figure out what the best way to get bergamottin is. I don't actually want to chug 2L of juice, especially when Valerian is already listed on Wiki as a "moderate inhibitor. I have bottles of Delsym, and I'm gonna go get some HBr products, tbd in the aisle. I have to see my mom today, but maybe I'll get at this tonight? I sure hope so. I'm fucking stoked. I'll probably just have to skip the â ˆ ‘ express experiment for now and just go for 1, superpotentiated dose. I'll be back. You too Kerflap. Don't forget about this shit. Drop a quick line sometime this evening. I wanna know how it's going.
318092>> 318094>>

>>
Kerflap !HUZ.4c6SGE - Fri, 29 May 2015 12:48:41 EST ID:3vHvRt9a No.318092 Ignore Report Quick Reply
>>318089
going into the next day.... this is weird to do. nb cause I wanna nb.

>>


>>
guythatpissedingrapefruitjuicebottle !7hqGpmbsrA!!booSESQR - Fri, 29 May 2015 14:19:34 EST ID:8ej+wX6e No.318094 Ignore Report Quick Reply

>>318089
hm maybe I understand it wrong but this seems actually pretty simple
the first dose on the left gets mostly metabolized into DXO and a little 3MM
As we now 3MM has a higher affinity to the P450-2D6 enzyme which converts DXM to DXO
thus the second dose on the left graph will result in a higher 3MM conversion then before and DXM gets metabolized slower because of this which will result in a potentioation effect
the right graph is basically the same but instead of two doses you have alot of small doses which leads to an even higher 3MM conversion rate and an even higher potentiation effect
correct me if I am wrong
318095>> 318634>>

>>
guythatpissedingrapefruitjuicebottle !7hqGpmbsrA!!booSESQR - Fri, 29 May 2015 14:22:30 EST ID:8ej+wX6e
also I figured that the best dosing regime is probably a bigger starter dose at the beginning followed by alot of small doses spaced out for maximum effects
hm never tried this but I just arrived back home with 10g of pure DXM pellets from Czech and I have whole next week free so I guess I have to do tests for science
318106>> 318140>> 318189>>

>>
guythatpissedingrapefruitjuicebottle !7hqGpmbsrA!!booSESQR - Fri, 29 May 2015 17:08:47 EST ID:8ej+wX6e
>>318095
guess I am bored and trying this now with 360mg DXM in total
dosing scheduel:
t 0 90mg DXM pellets
t +15 60mg DXM pellets 150total
t +30 45mg DXM pellets 195total
t +45 30mg DXM pellets 225total
t +60 30mg DXM pellets 255total
t +90 30mg DXM pellets 285total
t +120 30mg DXM pellets 315total
t +150 45mg DXM pellets 360total

just a low dose to see how it will compare to my usual scheduel of downing everything in 30minutes

already have 150mg in my system along with 500ml WGFJ that I drank two hours prior
318114>>

>>
Ebenezer Gillerham - Fri, 29 May 2015 17:59:39 EST ID:8ej+wX6e No.318114 Ignore Report Quick Reply
>>318106

this legietemately feels like a hallucinogenic version of MDMA
I haven't ever been that stimulated from DXM before
also only about an hour and 270mg into it and already having very slight CEVs I usually don't get this from such a low dose
and I haven't even smoked my weed yet
this looks promising
318121>>

>>
guythatpissedingrapefruitjuicebottle !7hqGpmbsrA!!booSESQR - Fri, 29 May 2015 18:38:25 EST ID:8ej+wX6e No.318121 Ignore Report Quick Reply
>>318114
can't remember when I had last tripped that hard on only 300mg DXM shit is SLAYER
318124>>

>>
Poopster - Fri, 29 May 2015 19:05:21 EST ID:7E2Ao8k0

Yo thanks bro. Ive wanted to try this stuff but dont wanna fuck my brane, even though i know a lot of organ healing techs. One time I drank almost a full bottle of tussin, and started feelin kinda drunk and good, then i felt violently ill and threw it up. Will continue to lurk. thanks for helpin a rookie.
318123>>

>>
Poopster - Fri, 29 May 2015 19:17:06 EST ID:7E2Ao8k0 No.318123 Ignore Report Quick Reply
>>318122

To add, I want to find out if this is even something worth doing, ya know? I would like a unique experience that might make me a better person in some kind of way. But I dont want to damage my body severely. i find that just about all drugs can give us some kind of trancendent experience. Exceptions include extasy, opiates and tobbaco. I have found these drug types to be whack and pointless. Im still on the fence and igorant about This board, Benzos, Deliriant and Jenk. Things I havent tried yet.....Jenk seems like some kinda troll or joke board tbh.

>>
guythatpissedingrapefruitjuicebottle !7hqGpmbsrA!!booSESQR - Fri, 29 May 2015 19:18:45 EST ID:8ej+wX6e
prolonged this because this worked so great no negative side effects either
450mg so far and raising
shooting for a 4th
I knew this day would come
and I knew that I would know when it's time
318184>>

>>
Fiend !!1C9jE+w+ - Fri, 29 May 2015 21:41:47 EST ID:u4P4AARV No.318140 Ignore Report Quick Reply
>>318095
Other way round. Start small and get your enzymes working. Keep up a steady flow of inhibitors. Then introduce a bunch of DXM at once and your liver'll be like "wut?" That's how to get to ∑. Starting big and adding little bits is how you get to colored void, or ;) in other nomenclature ∏(3,2).

NCACEDEADDEL - Sat, 30 May 2015 00:50:32 EST ID:Q2Pud5XC No.318164 Ignore Report Quick Reply
>>318055

Okay, now I have to tell you this. So, MAYBE infrasigma is "not able" to be obtained by taking triple c's for days and weeks on end, and only triple c's but...can it be seen as close to that level of infrasigma if one were to do such?

I had a period in my life where I was doing triple c's as much as I possibly could, at most maybe a little at most over 32 pills in 24 hours ( 30 mg dxm HBR + what like 4 mgs of CPM? Anyways) I once had a spazz attack and litterally thought I was dead/dying/going through thought loop motions so badly that I not only had to go to the hospital from blacking out (sort of not really, kind of because that is just how it went down and I did not want to try to explain my sanity any longer to the people I was living with so I was like fuck it I'm done rage mode) now, I have psychosis very badly and always will......started at a very young age I could tell it was quite educate to safely safe I was succeptible to psychosis at as a youngin. What I am trying to get to is I get what you mean in some ways about the energy fields, rolling, yada yada ect, because the night I felt I was dying from only 8 triple c's (remember how often I was using & what is in them! ) I could have sworn left and right that at one point A. physcial movement was keeping myself alive such as tapping my fingers or anything and B. at another point, my "light body" energy was very very very easily controlled to keep myself alive, LET ME PUT IT LIKE THIS. Imagine sitting criss cross legged on the floor, you are having a freak attack feeling like you are dying and all the sudden !!! You feel the energy around you and inside you like it is nothing, I could control my spiritual or energetical I.E. Electrical current inside my body, maybe life force, it was bouncing around and zapping every way I mentally moved it....Have you ever been tripping and seen/experienced time move backwords and forwards simultaneously? Even audio that you are speaking and hearing?...Almost like you were pre-predicting what was going to happen next based on what you believe most and thought/think/"control" what is going to happen? Now you might be sitting here thinking well duh of course we have choice although yet I am refferencing actions of other people as well, predicting/prophesying "that" which we move together as one whole, if you know DXM very well you know damn well how CPM and DXM differnciate each one to the other and can tell what you are feeling, for real.. Blessings, less redrum, stay safe, careful and do ONLY what y'all want and choose to, it is your life to live over and over how ever which ways you please, make now count though this is why y'all here now folks S/O from /DEL/ , reply anyone? Love to talk...I am lucky I am still talking at all... Seriously, even a word shouldn't be coming from myself for what I have been through. Goodnight
318187>> 318198>>

>>
guythatpissedingrapefruitjuicebottle !7hqGpmbsrA!!booSESQR - Sat, 30 May 2015 05:39:51 EST ID:8ej+wX6e

if any one cares I stopped after 600mg after I read Fiends post
I had the best and most clear and high defined CEVs I have ever gotten from any drug last evening
When closing my eyes it was as if I was entering another realtiy and was hoovering through a forest and could see every small detail of every leaf or tree but the colors where off and rainbow like (like in pic related)
Although it felt like a 3rd plat when peaking it was noticeably different from my usual trips
it was much more speedier especially in the beginning
it was one of my most intense and most beautful expireinces I ever made
also the afterglow feels different not as lethargic but rather like I sniffed some amphetamine pared with a slight weed feeling
318186>> 318198>> 318405>>

>>
Kerflap !HUZ.4c6SGE - Sat, 30 May 2015 07:39:18 EST ID:3vHvRt9a No.318186
Been doing this since my post. I missed one dose yesterday but hit the next dose after it so I think I'm good. Been taking garlic and triple C to potentiate. God damn, this shit REALLY fucks you up good. will right a report later.

Fiend !!1C9jE+w+ - Sat, 30 May 2015 12:56:33 EST ID:u4P4AARV No.318198 Ignore Report Quick Reply
1433004993825.jpg -(9194 B, 400x354) Thumbnail displayed, click image for full size.
>>318164
> Have you ever been tripping and seen/experienced time move backwords and forwards simultaneously?
> Even audio that you are speaking and hearing?...Almost like you were pre-predicting what was going to happen next based on what you believe most and thought/think/"control"
Holy shit yes! I had never really thought about it in those words, but goddamn that is exactly what started happening on day 3. The way all matter was unstable, so was time. Things could be in two places at once as I said, but that applied to time as well as space, and I hadn't thought about that. Like I was experiencing a 3 second interval all at once, always, and it was constantly sliding, not interval over interval, but rather, like, the sliding block on a beam balance, center of balance in one place that moves linearly, but the weight itself takes up space in both directions. Pic related I was in the entire circle at once. And my perception of it would flit from location to location (in time), kinda like the double-split experiment; but in the same way it was only when I tried to observe it. Otherwise it existed as both at the same time.

>>318184
> I had the best and most clear and high defined CEVs
> When closing my eyes it was as if I was entering another realtiy and was hoovering through a forest and could see every small detail of every leaf or tree
I was worried my "colored void" analogy wouldn't make sense sense to anyone else. But ding ding! We have a winner!

>>318186
> I missed one dose yesterday
> God damn, this shit REALLY fucks you up good.
I think you're good. :)

I did all the potentiator crap yesterday. It was pretty fucking awesome. Afterglow is different. I think Fallen was totally onto something with the HYM being more active than previously thought. But I spent too much time on this post already. I have to go make breakfast. I'll be back with a more thorough report.
Fiend !!1C9jE+w+ - Sun, 31 May 2015 11:49:57 EST ID:u4P4AARV No.318265 Ignore Report Quick Reply
>>318093
>>318198
Fuck. I'm so not in the mood to do a whole explanation. Long story short
> 11:00am
My Rx meds, which includes 50mg Hydroxyzine
> 2:00pm
Ate 1 grapefruit. I left the other 2 at home though so I didn't get to eat them.
> 3pm
Drank ~1.5oz Delsym (call it 300mg DXM poly to be simple. Took another 50mg Hydroxyzine because I wasn't sure if I took in in the morning.
> 5:30
200mg Cimetidine
> 7:30pm
100mg Hydroxyzine + 100mg DPH + 25mg Doxylamine + ~2.5oz Delsym (call it 420mg poly because fuck you that's why)
> 8:15-8:30-8:45
knocked back a 4oz Tussin (354mg DXM HBr) in 3 doses.
> 9pm
4Cs (120mg DXM HBr + 16mg CPM)
> 10pm
Realized I forgot the Valerian. Took 2.12g.

I was reminded of the first few times I did DXM. The real deal robowalk. Everything looking droopy and ghetto. So much solipsism. It kinda felt like it brought back all the magic I didn't know I had lost. And it lasted and lasted. I didn't even start coming down until like 2am. And when I woke up at 11, and came here to post, all of a sudden I realized I was still tripping when my whole head started swimming with the strain of looking at text and trying to compose my own response. It was probably 2-3pm before I felt sober enough to drive.

The one drawback of this experiment was that I totally overdid it with the antihistamines. It may have made the DXM fucking beautiful, but it corrupted the shit out of the afterglow. By the evening the dex-glow was cut and I was left with /del/ vibes of abject suicidal ideation. The dex kelpt me calm, so the ideation wasn't violent or anything. I was very much in control, but I still kinda couldn't get it out of my head; and I was irritable for most of the day. It took me until significantly after dinner to shake the solipsism. I had to like stare into my dog's eyes, and pet her, and talk to her, before she pawed me, and I found myself re-convinced that other conscious beings probably exist.
318270>> 318548>>

>>
Phyllis Buzzman - Sun, 31 May 2015 13:49:53 EST ID:DS1By1JP No.318270 prepared my enzmymes today took 30mg every hour for 5 hours what will happen if I drop 450mg now?

Jonny - Sun, 31 May 2015 18:28:24 EST ID:6+gyyB8i No.318289 Is a plateau sigma trip a trip on dxm or dxo? And what about I infrasigma? Or is one or both of them a balance? Understandably I'd feel stupid, it seems like I'm missing one two or crucial parts of this.
I've tried Plateaus 1-4countless times. I'm yet to try sigma and I'd prefer to try infra.

I have two big cartons of grapefruit juice and a good amount of DPH. I'm guessing Garlic turned out to be a dud?

Anyways Im taking week off of sexing and then I'm going to plan to go for infrasigma unless someone thinks I should try sigma first. Ill probably start dosing on Thursday.

Jonny - Sun, 31 May 2015 23:44:02 EST ID:Z4/mhthx No.318322

PS if Sigma is essentially DXM, then what is infrasigma? It sounds like they're the same thing?

PPS I always noticed I experienced psychedeliclike effects the morning after a high dose of DXM. Why do you suppose this is?
As in flowing patterns on walls, increased sense of touch, increased feeling of music, etc.
318331>>

>>
Fiend !!1C9jE+w+ - Mon, 01 Jun 2015 01:24:18 EST ID:yZ631VIJ No.318331 Ignore Report Quick Reply
1433136258919.png -(71117 B, 1140x998) Thumbnail displayed, click image for full size.
>>318322
Okay. Previously I came up with a plateau system that's like 2D coordinates. DXO is on the X axis. DXM is on the Y axis. Any standard single dose will lead to almost all DXO, and the plats we know would be written ∏(0,1) ∏(0,2) ∏(0,3) ∏(0,4). As enzyme inhibition increases, you get more DXM in relation to DXO. For instance I've never really hit a standard 4th plat exactly. I always black out. But slow-dosing I was able to reach a place I'd tentatively call ∏(3,2) which has radius 3.6 if you wanna think of it that way. Anyway, Sigma, anything above the line (in the pic) is the Sigma Realm. What Mr. White dubbed "Plateau Sigma" or what I'll call full sigma, would probably be ∑(2,3). What cursive coined "Infrasigma" would probably be ∑(Ø,1). But honestly by the end of day 3 I'd say I was closer to ∑(Ø,2), maybe even ∑(1,2), places that are all in the Sigma realm. And I've done other binges of ∏Ø doses that landed me at different places on the graph. I think it's a way better way of quantifying the Dex experience (to avoid calling it DXM and re-confusing everything I just said).

As for the afterglow, Fallen's theory was that that might actually be HYM (see the graph from >>317835 ) but that's even deeper in the realm of speculation than most of this.
318369>>

>>
Ωµæ§†♪α¡ⁿ - Mon, 01 Jun 2015 03:02:05 EST ID:7fJS5VhP No.318337 Ignore Report Quick Reply
I've been thinking some, and I could be totally off, but couldn't you say that infrasigma is simply sigma without taking trip-doses? For instance, to hit sigma you repeatedly dose large amounts (compared to medicinal dosages) and on the way you will rise past first, second, maybe third and fourth plateaus, until you eventually sigma. So infrasigma would be similar in the way that you are going to hit sigma plateau but you are never taking enough to actually induce the lower plateaus, instead skipping them all and going straight for the prize. Does this make sense? Too much thought-incest in my sober mind for me to really be able to better explain.
318365>>

>>
Kerflap !HUZ.4c6SGE - Mon, 01 Jun 2015 06:44:38 EST ID:3vHvRt9a No.318345 Ignore Report Quick Reply
I still am not ready to write out a trip report. I am still tripping heavily and haven't dosed in about 36 hours. This trip was EXTREMELY intense, EXTREMELY dark, and in no way meant for light hearted people. The way you need to dose for days on end is tiring, the thought of more chemicals entering the body is disgusting, but yet you want to continue just so you can see what it is like.

I spent the majority of this trip watching movies, and most of the movies I watched were strangely oriented toward death and depression. Some of the movies I watched were trainspotting, Maniac (first person slasher film), A fantastic fear of everything (movie where a guy fears everything), the mirror (pretty much an oculus clone), the new madmax (saw it in theaters), and finally enter the void.

Night before last, I took a full 5oz delsym spilt half and half hour hour before seeing mad max and then about 5 hours after that I did the same thing, another 5oz delsym split half and half an hour before dosing, and as I got home my friend gave me back my pipe I let him borrow to smoke DMT. Well, I grabbed my knife, scrapped my pipe, and wound up having a nice huge pile of DMT in my pipe I could smoke. I dosed my last swig of delsym, smoked some weed, and then smoked some DMT just as I turend on enter the void, literally having no idea what enter the void was about and watching it only on recommendation of friends.

The DMT seemed to have made me go into some sort of realization. Somewhere way too fucked up to be sober but way too sober to be fucked up. I could not get over the overwhelming sense that the main character in the movie looked literally EXACTLY like me to the tiniest detail. I was in the perfect mindset to view this movie and take it in exactly as it was meant to be seen. Everything made sense, every detail was made clear, nothing slipped past me, and I watched it twice to be sure. Needless to say, this trip was the most intense trip I had ever had with DXM, and I'm not sure if I exactly ever want to do this again to this level. This was at times more scary than it was fun to me, and other times more interesting than it was trippy, but no doubt this was the most complete trip on DXM I had ever had.

I'll prolly finish out these last 6 triple C today and smoke some bud and then call it an end to my trip after that. This was intense, way more intense than I had anticipated.

I'll answer any questions anyone has about this if you ask them. Feel free to ask away and I'll answer to best of my ability.

>>
Kerflap !HUZ.4c6SGE - Mon, 01 Jun 2015 06:44:38 EST ID:3vHvRt9a No.318346 Ignore Report Quick Reply
I still am not ready to write out a trip report. I am still tripping heavily and haven't dosed in about 36 hours. This trip was EXTREMELY intense, EXTREMELY dark, and in no way meant for light hearted people. The way you need to dose for days on end is tiring, the thought of more chemicals entering the body is disgusting, but yet you want to continue just so you can see what it is like.

I spent the majority of this trip watching movies, and most of the movies I watched were strangely oriented toward death and depression. Some of the movies I watched were trainspotting, Maniac (first person slasher film), A fantastic fear of everything (movie where a guy fears everything), the mirror (pretty much an oculus clone), the new madmax (saw it in theaters), and finally enter the void.

Night before last, I took a full 5oz delsym spilt half and half hour hour before seeing mad max and then about 5 hours after that I did the same thing, another 5oz delsym split half and half an hour before dosing, and as I got home my friend gave me back my pipe I let him borrow to smoke DMT. Well, I grabbed my knife, scrapped my pipe, and wound up having a nice huge pile of DMT in my pipe I could smoke. I dosed my last swig of delsym, smoked some weed, and then smoked some DMT just as I turend on enter the void, literally having no idea what enter the void was about and watching it only on recommendation of friends.

The DMT seemed to have made me go into some sort of realization. Somewhere way too fucked up to be sober but way too sober to be fucked up. I could not get over the overwhelming sense that the main character in the movie looked literally EXACTLY like me to the tiniest detail. I was in the perfect mindset to view this movie and take it in exactly as it was meant to be seen. Everything made sense, every detail was made clear, nothing slipped past me, and I watched it twice to be sure. Needless to say, this trip was the most intense trip I had ever had with DXM, and I'm not sure if I exactly ever want to do this again to this level. This was at times more scary than it was fun to me, and other times more interesting than it was trippy, but no doubt this was the most complete trip on DXM I had ever had.

I'll prolly finish out these last 6 triple C today and smoke some bud and then call it an end to my trip after that. This was intense, way more intense than I had anticipated.

I'll answer any questions anyone has about this if you ask them. Feel free to ask away and I'll answer to best of my ability.
318348>> 318365>>

>>
guythatpissedingrapefruitjuicebottle !7hqGpmbsrA!!booSESQR - Mon, 01 Jun 2015 06:59:49 EST ID:DS1By1JP No.318348 Ignore Report Quick Reply
>>318346
did you slepp at all?
I couldn't see myself doing this since I always get insomnia when taking DXM and over that period of time it would be torture
318350>>

>>
Kerflap !HUZ.4c6SGE - Mon, 01 Jun 2015 07:09:53 EST ID:3vHvRt9a No.318350 Ignore Report Quick Reply
>>318348

I slept very little. just a couple hours at a time at most.
318351>>

>>
Isabella Poblingstock - Mon, 01 Jun 2015 07:21:46 EST ID:7oTkxFzg No.318351 Ignore Report Quick Reply
>>318350

How was the nausea? I get it bad even when im taking doses as low as 300mg, but noticed it gets easier if you redose. Did it just get to a point where taking more dxm didnt have any nausea?

Also how much have you eaten during this trip? I could barley get down a slice of bread during the last 3rd plat I did.
318352>>

>>
Kerflap !HUZ.4c6SGE - Mon, 01 Jun 2015 07:49:20 EST ID:3vHvRt9a No.318352 Ignore Report Quick Reply
>>318351
I didn't have any nausea really through out, and I normally don't get nausea. I ate very little throughout this trip. just little bits here and there. my stomach kinda hurts.

god, this auditory hallucinations are crazy as fucking hell. I hear a constant whistle in my left ear, in my right I hear a woowoowoowoowoo, in the left I hear tv static too, in the right I hear clicking, in the left ticking. it's constant. I smoked and this started up. Now my chest feels like it weighs a hundred pounds and my vision is completely fucking sparkles. it's so fucking hard to see. this is fucking crazy. I don't know how to explain anything right now. god... Sorry, this is all coming from my head as I speak, live trip reporting. now I hear explosions. All this noise I hear, it comes from inside my head. i hear it in my hears from inside my head. like the noise is happening on my brain. everything is jumping around. this is the most intense trip I have ever had from any drug in my entire life. that DMT I smoked fucking ramped this up. I could possibly get one more hit too. Should I?

Fiend !!1C9jE+w+ - Mon, 01 Jun 2015 12:03:43 EST ID:yZ631VIJ No.318365 Ignore Report Quick Reply
>>318337
Sigma is NOT a plateau. See >>317806 & >>317906 There is no "passing" the other plateaus. That's why I made a 2D graph. If the standard plateaus are on the x axis, ∑ is just somewhere else (the y axis).
>>318346
> The way you need to dose for days on end is tiring, the thought of more chemicals entering the body is disgusting, but yet you want to continue just so you can see what it is like.
> more interesting than it was trippy,
> but no doubt this was the most complete trip on DXM I had ever had.
Yes. Yes. Go on.
> god, this auditory hallucinations are crazy as fucking hell.
> I hear a constant whistle in my left ear, in my right I hear a woowoowoowoowoo,
> in the left I hear tv static too,
> in the right I hear clicking, in the left ticking.
> it's constant.
> my vision is completely fucking sparkles.
> All this noise I hear, it comes from inside my head.
> i hear it in my hears
> like the noise is happening on my brain.
> everything is jumping around.
Kerflap! Fuckin A+ my friend! I'm actually cackling maniacally. You + cursive + I makes 3. That's what's fucking called proof of concept, bitches! Ha! Ha HA! Fucking awesome. Someone please screen cap this fucking thread and put it somewhere more permanent.

... [whispers] ... <∑ ...
318366>>

>>
guythatpissedingrapefruitjuicebottle !7hqGpmbsrA!!booSESQR - Mon, 01 Jun 2015 12:09:42 EST ID:DS1By1JP No.318366 Ignore Report Quick Reply
>>318365
you said I expirienced ∏(3,2) or colored void when I did this dosing expiriment with starting big adding alot of small doses do you have some infos on that
because I can't seem to find anything at all
318368>>

>>
Fiend !!1C9jE+w+ - Mon, 01 Jun 2015 12:14:46 EST ID:yZ631VIJ No.318368 Ignore Report Quick Reply
1433175286203.jpg -(1305358 B, 1275x1650) Thumbnail displayed, click image for full size.
>>318366
It's terminology I made up completely myself. It's not on the internet lol. Here's the original document.
318374>>

>>
Fiend !!1C9jE+w+ - Mon, 01 Jun 2015 12:15:53 EST ID:yZ631VIJ


NOTE: A lot of what Fallen taught us, means that this is founded on bullshit assumptions about DXM metabolism and it leaves out the whole possibility of MEM and HYM being active and blah-di-blah-di-blah (I'm getting really tired of disclaimering myself, as if I have to remind people I'm only fucking human. Fuck). But I hope the nomenclature makes sense...

>>
guythatpissedingrapefruitjuicebottle !7hqGpmbsrA!!booSESQR - Mon, 01 Jun 2015 12:26:27 EST ID:DS1By1JP No.318374 Ignore Report Quick Reply
>>318368
lol but this shit holds some thruth otherwise I wouldn't have seen what I did
318377>>

>>
Fiend !!1C9jE+w+ - Mon, 01 Jun 2015 12:46:29 EST ID:yZ631VIJ No.318377 Ignore Report Quick Reply
>>318374
I mean, do you kinda understand what I'm trying to get across? Like, having done that dosing regimen, and knowing that DXM is fucking wacky (less NMDA etc... fuck) compared to DXO, and thinking about like slamming a 3rd plat HBr dose, which I found to be kinda colorless. My first 3rd plat I called it The Greyspace; kinda the way a K/M-hole are without /psy/s. DXM is what people point to as more /psy/chedelic than DXO; anyway. Like, all that considered. Can you get behind the idea that ∏(3,2) is a good description of what you experienced, in relation to the standard 4 ∏s?
318380>>

>>
guythatpissedingrapefruitjuicebottle !7hqGpmbsrA!!booSESQR - Mon, 01 Jun 2015 13:05:34 EST ID:DS1By1JP No.318380 Ignore Report Quick Reply
>>318377
yes definitely I actually came up myself with that dosing regimen you just called it "colored void"
I tried many different methods and additives but found that its best to let some DXM block your enzymes and when you want to start your trip drop your dose or dose slow
the initial dose then specifies how the the trip is gonna be
start big, alot of small "colored void"
start small, prolong small, drop alot "sigma"
there is somthing interesting about DXO DXM ratio and it might be alot more decisive then we might thought because no other drug in existance requires such a strange dosing regimen
318381>>

>>
Fiend !!1C9jE+w+ - Mon, 01 Jun 2015 13:27:28 EST ID:yZ631VIJ No.318381 Ignore Report Quick Reply
>>318380
> no other drug in existance requires such a strange dosing regimen
It's not required. How you dose is completely optional, and incredibly variable. That's the best part. Dissociatives in general though get seriously fucked if you redose for long enough, as anyone who's done ≥10 bumps of MXE in ≤12hrs can probably attest to. 3-MeO-PCP has it's own fucking insane version of ∑ that I've been to like twice. Hell, even Nitrous gets its own version of sideways up-fucking after a while (See the /dis/ achievement At least 100 whippets ago ). DXM is very special in that we have 2 distinct metabolic pathways and 2 or more active metabolites, but I think it's not completely unique. Some shit starts to happen when you stay dissociated for extended periods of time, regardless of the substance. Whether there is a neurochemical explanation about NMDA antagonism, or if it's just that being that fucked for that long makes you stallionoo, IDK... Fuck. I really can't think straight today.

guythatpissedingrapefruitjuicebottle !7hqGpmbsrA!!booSESQR - Mon, 01 Jun 2015 21:53:10 EST ID:DS1By1JP No.318422 Ignore Report Quick Reply
>>318381
where am I? tell ma
took 30mg DXM every hour for 5 hours this morning then continued to ingest 30mg DXM every 2hours over the course of the day 90 in total
then I dropped 450mg wthin 30minutes
this feels so clean its like the sativa of DXM dont know hpw to desscribe
318425>> 318534>>

>>
Fiend !!1C9jE+w+ - Mon, 01 Jun 2015 22:11:24 EST ID:yZ631VIJ No.318425 Ignore Report Quick Reply
>>318422
IDK. You tell me. 30mg is antitussive dose. Don't know how much that affects things. Don't know how much you weigh, don't know you're tolerance. I can't tell you where you are. I invented a language so that you could tell me.
318427>>

>>
guythatpissedingrapefruitjuicebottle !7hqGpmbsrA!!booSESQR - Mon, 01 Jun 2015 22:13:21 EST ID:DS1By1JP No.318426 Ignore Report Quick Reply
>>3184do you know that film "limitless"?this feels exactly like what you can see in the movie right now
crazy it's like a complete psychological high no body stoned at all
318435>>

>>
guythatpissedingrapefruitjuicebottle !7hqGpmbsrA!!booSESQR - Mon, 01 Jun 2015 22:16:17 EST ID:DS1By1JP No.318427 Ignore Report Quick Reply
>>318425
60kg light tolerance
318428>>

>>
guythatpissedingrapefruitjuicebottle !7hqGpmbsrA!!booSESQR - Mon, 01 Jun 2015 22:17:18 EST ID:DS1By1JP No.318428 Ignore Report Quick Reply
>>318427
I meant a low tolerance

>>
cursive !M6R0eWkIpk - Tue, 02 Jun 2015 01:22:59 EST ID:Dmczvq8n No.318435 Ignore Report Quick Reply
>>318426
i fuckin told ya.
318444>>

>>
guythatpissedingrapefruitjuicebottle !7hqGpmbsrA!!booSESQR - Tue, 02 Jun 2015 04:55:55 EST ID:DS1By1JP
what did you tell?
man yeasterday was just wow DXM is a drug like no other
I did a strong LSA trip some weeks and it is a joke compared to this
I slept like 5 hours tonight and I am still tripping hardcore
318445>> 318513>>

>>
guythatpissedingrapefruitjuicebottle !7hqGpmbsrA!!booSESQR - Tue, 02 Jun 2015 05:17:08 EST ID:DS1By1JP No.318445
>>318444
oh no just saw we gonna get 30°C (80F) today this is gonna suck
318446>>

>>
Fucking Fabberford - Tue, 02 Jun 2015 05:44:50 EST ID:DS1By1JP No.318446 Ignore Report Quick Reply
>>318445
I have never felt so alive this is indescribable
318465>>


On another note, I seem to recall reading someone in this thread saying he or she was combining ginger with DXM though I'm not sure where. Is it safe? Is it useful for potentiation or for clarity of thought or both?

Suppose I can just Google it but what's y'all's experience if any?
318505>> 318521>>

Jonny - Tue, 02 Jun 2015 22:52:21 EST ID:Z4/mhthx No.318506 Ignore Report Quick Reply
>>318505
Gingko rather, autocorrect error

>>
Kerflap !HUZ.4c6SGE - Wed, 03 Jun 2015 00:48:42 EST ID:3vHvRt9a No.318512 Ignore Report Quick Reply
>>317782 (OP)

God damn... woke up today still buzzing and haven't taken anything in soo long. still not completely sober. I'm just drinking now. Fuck man, that was intense and not exactly pleasant. Extreme paranoia all the way through towards the end, felt like I was dying. Some for sure the most extreme and complete DXM trip I'd ever had for sure though. Most likely will not repeat.
318524>> 318526>>

>>
cursive !M6R0eWkIpk - Wed, 03 Jun 2015 00:58:56 EST ID:Dmczvq8n No.318513
dude literally rave like a lunatic about dxm superpowers in real life whenever it comes up and on this no joke pretty much every time i post which is all day evwryday for two years, specifically mentioning Limitless and  Lucy.
also totally went batwing commander blindfolded through my house on youtube.
shit at least now you're limitless homie , cause it sucked seein you junkin around so long. step up dude. become based questor
and ps youre fuckwd for life now

>>
guythatpissedingrapefruitjuicebottle !7hqGpmbsrA!!booSESQR - Wed, 03 Jun 2015 05:23:08 EST ID:DS1By1JP
>>318512
holy shit my sigma expiriment is over finally
just looked at my posts from yesterday lol
apearently I built an AC in a psychotic induced DXM phase and posted in on 420chan
god damn it lieterally felt like I went schizoprenic when I was tripping this was too much and still have 2g DXM left but I think I going to abstain from it for a very long time

>>
maybe, but fuck, the DMT trip never fucking left! The rest of my entire trip was filled with DMT! It was as if my brain kept hold of the DMT and never let it go. Smoking still brings back residual effects. The weirdest thing during the entire trip though, has to be that my chest felt like it weighed a ton. it felt like my heart was a 30 pound weight.
318544>> 318545>> 318548>> 318571>>


Jonny - Wed, 03 Jun 2015 13:45:11 EST ID:Z4/mhthx No.318545

Also, have been dosing 30mg DXM and 4mg CPM per hour since nine this morning.
While on my bike ride I noticed some insane thoughts. I label them under 'insane' for several reasons:
They were loud

Who's listening anyway?

3.Who's doing the speaking?
4. Causality credited to afterglow from last night's trip in addition to the possibility of encroaching nonsensical thought patterns, if not psychotic, if not sociopathic, probably none of the above except for nonsensical because

I'll make dutifully sure to keep on keepin' on throughout the day and slice myself a good sliver of running tally taffy. For the Endgame.
318548>>

>>
Fiend !!1C9jE+w+ - Wed, 03 Jun 2015 14:23:26 EST ID:yZ631VIJ No.318548 Ignore Report Quick Reply
>>318534
> I'm understanding that, in my lack of understanding, I'm not far behind anyone else in grasping the exact metabolic processes.
Dude, I know you got this. From what I can tell you're smarter than most of the people on this site; and I'm gonna keep yelling at you until I see you, just once, dare to believe that you know things.
>>318542
I wrote about it. >>318265
>>318543
Interesting. I've noticed that DXM extends the effects of Nitrous and Salvia for a really long time. I was interested in if this would apply to DMT. You say it stuck around not just 30 minutes long, but the whole rest of the trip? Fucking cool. Wonder what that's about.
>>318545
> They were loud
> Who's listening anyway?
I'm fucking serious! Stupid people don't have thoughts like that! Stupid people don't write interesting things about interesting thoughts they had! Shit!
And word. 30mg an hours is way slower dosing than I was ever thinking. It sounds like you're reaching Ø though.  Keep in touch.
318557>> 318672>>

>>
Jonny - Wed, 03 Jun 2015 16:50:19 EST ID:PWfcgpcA No.318557 Ignore Report Quick Reply
>>318548
I reached this state of mind where I was trying to think of a certain material, somewhere between those thick metal cords used for bridges, human tendons, and cellophane. it's this substance in my mind, the more I try to describe it, the less sense I begin to make. For example, I could say, to describe this substance we would imagine ourselves approaching it from a distance, and during the approach it would be like entering the sensation of greeeeeeeeen. Like the color, but not just regular green, it has to be greeeeeeeeen.

Anyways, I could go on and on about materials I feel in my mind on DXM but its sadly difficult to make sense of verbally. Sadly, because it feels important, because it literally has to do with both the end and the beginning of the universe. I mean it, honest to God.

Anyways, in this state, I fell asleep unfortunately. I missed one or two doses of 30mg. Took my four o'clock and three o'clock is incoming. Five rather.

Honestly Fiend you're just too nice for your own good. I mean I love you man, but you gotta let a guy engage in some healthy self-deprecation every now and then. It's good for the Soul Roots.

Anyways, I could get stranger and stranger as the day stretches thin, but at the end of it all, alas, just as this chunk of eraser holding my earring in is no more than an emblem of falsehood, so shall I depart on the morrow no more a man than a shade and no less a shade than a far-off symbol of my own departure.

Jack Grimshit - Thu, 04 Jun 2015 08:39:01 EST ID:ANdTithf No.318609 Ignore Report Quick Reply
>>317806
I can't believe nobody's ever thought of the 3-MM theory before that's freaking GENIUS
318613>>

>>
Fiend !!1C9jE+w+ - Thu, 04 Jun 2015 10:23:53 EST ID:yZ631VIJ No.318613 Ignore Report Quick Reply
>>318609
Yeah. I know, right? Like how did nobody think of that? Someone had to be like "well so theres DXM, which is broken down into DXO & MEM Then that shit get's metabolised into this shit called 3-MM, but that's probably not active, so don't worry about it."
318619>>

>>
Jonny - Thu, 04 Jun 2015 12:17:03 EST ID:/FXBGNvi No.318619 Ignore Report Quick Reply
>>318613
So this 3-MM....
318620>>

>>
Jonny - Thu, 04 Jun 2015 12:23:55 EST ID:Dq9QFOxO No.318620 Ignore Report Quick Reply
>>318619
Although it may seem the cat got my tongue in fact that was the entire question sans question mark sans context, Google has not the dignity to lend me even the smallest truth concerning anything 3-MM related, unless the thing is is three millimeters long.

Also going over this thread I was unable to spot l those two idiosyncratic symbols and one numeric emblem and (punctuation mark?) hyphen in the correct order.
318634>>

>>
Fiend !!1C9jE+w+ - Thu, 04 Jun 2015 15:24:58 EST ID:yZ631VIJ No.318634 Ignore Report Quick Reply
1433445898248.png -(685885 B, 1892x1268) Thumbnail displayed, click image for full size.
>>318620
Fallen, and the graphic from >>318094 call it HYM. (Here's a better graphic) It's the final (as far as we know) metabolite of DXM. DXM is broken down into two drugs, DXO and MEM, by 2 different metabolic pathways. One, (CYP2D6) chops of the O-methyl group giving you DXO. The other (CYP3A4) chops off the N-methyl group, giving you MEM. The enzymes then switch targets. So MEM gets it's O-methyl group chopped off by 2D6, and DXO get's its N-methyl group chopped off by 3A4, both pathways leading back to HYM (3-MM in other nomenclature).
318639>> 318642>>

>>
guythatpissedingrapefruitjuicebottle !7hqGpmbsrA!!booSESQR - Thu, 04 Jun 2015 16:17:12 EST ID:1r8B2rls No.318639 Ignore Report Quick Reply
>>318634
and MEM has a higher affinity to bind with the CYP2D6 enzyme so the more MEM you have the less DXM get converted into DXO which makes it possible to potentiate DXM by itself when taken spaced out
just wanted to add my two cents nb
318683>>

>>
Jonny - Thu, 04 Jun 2015 17:22:26 EST ID:Rb9KR/Ff No.318642 Ignore Report Quick Reply
>>318634
Oooh right I knew about HYM of course. It reminds me of church. It looks like basically DXM splits in half, or is pulled apart rather, by the two tugging forces of CYPD2D6 and CYPD3A4 enzymes, and then whorls about within a person and plunges through the blood brain barrier and eventually all the little MEMs and all the little DXOs do somersaults and form like Voltron back into HYM.

So basically when CYPD2D6 is inhibited, eventually it just gives up and let's half of the DXM through the blood brain barrier.
Now I have two questions to bring to the table in alphabetical order:
A. If inhibiting conversion of DXM into DXO allows DXM through the blood brain barrier, are there any CYPD2D6 or CYPD3A4 stimulants that would speed up the process enough that HYM is created near the beginning and slides through the blood brain barrier? Or rather, just to at least put us on a good track, are there any chaps that would strengthen the enzymes and make them work harder? Or would that not be what's needed in the first place?
C. Why is it always CYPD2D6 inhibition, why never CYPD3A4?
318643>>

>>
Fiend !!1C9jE+w+ - Thu, 04 Jun 2015 17:29:52 EST ID:yZ631VIJ No.318643
Slowing your metabolism (i.e. inhibiting the shit out of your enzymes), is the best way to get at HYM, and that will be in the afterglow period. Slowing the metabolism will just get the HYM to chill longer, and give you more time with it after the rest of the shit is gone). There's no way to increase the conversion to HYM without ... well wait a minute. Are you looking for C-P450 inducers? They might get you to HYM faster, but it also means you might be straight skipping the DXM high, as well as possibly increasing tolerance by metabolizing so rapidly. Perhaps you could take inducers to speed up DXM > HYM but then half way through, take a bunch of inhibitors and plug up your whole system and try to jam it to keep the HYM in. Hydrating minimally will keep it from being excreted in urine too quickly, but that's obviously simply unhealthy (as opposed to the rest of this which is complexly unhealthy, lol).
318653>>

>>
Jonny - Thu, 04 Jun 2015 19:34:40 EST ID:Z4/mhthx No.318653
I'll research indicates. Can you imagine? You speed up the metabolic process and then jam it, after an appropriate amount of time (an hour, four hours, a day?) And if the theory is correct then you get to enjoy an enhanced version of that lovely friendly state of mind where you see golden/silver sparkling patterns that look like wallpaper or banister and that gasoline swirl type vision. I absolutely love that shit.

Man today is a bad day because I have had snot in the back of my nose for hours and I can't clear it out no matter how much I snort or blow. It somehow gave me a stomach ache. Hopefully now that I'm getting dissociated, it'll leave me alone.

P.S. I'm hallucinating this blues rock guitar sounding out of my closet,like in Maggot Brain,but different tunes. Shits raw
318665>> 318666>>

>>
Fiend !!1C9jE+w+ - Fri, 05 Jun 2015 00:51:20 EST ID:yZ631VIJ No.318665 Ignore Report Quick Reply
>>318653
It seems really implausible considering the materials required. Better off riding HYM from afterglow.



>>
Terror Incognito - Sat, 06 Jun 2015 14:27:51 EST ID:R4en0hO/ No.318749
Ugh reading over this thread really really makes me want to trip again.

Considering 300 mg tonight for the first time in like 4 months... decisions, decisions.... But knowing me, I'll most likely re-dose twice like last time..



>>
Fiend !!1C9jE+w+ - Sat, 06 Jun 2015 16:10:30 EST ID:yZ631VIJ No.318756 Ignore Report Quick Reply
>>318749
I know. It's hard to see this thread (the OP pic is perfect btw) and not just want to go to all the pharmacies within 1/2mile radius and buy 2-3 DXM products from each one, and just go ∑ my fucking face off for a few days.
318774>>

>>
cursive !M6R0eWkIpk - Sat, 06 Jun 2015 16:12:54 EST ID:Dmczvq8n No.318757.
infra sigma throw back full bump

>>
Terror Incognito - Sat, 06 Jun 2015 18:19:40 EST ID:9adZbmcS No.318774 Ignore Report Quick Reply
>>318756

It just sucks because I'm trying to move to a new house and get my shit together and mostly just stick with weed. But then whenever I come to /dis/ the /dis/ gods are all screamin' at me like " YO NIGGA COME SHPANGLE HERE IN THE BRAINFOREST LMAO" and I'm just over here like "damn".